| Cat. No. |
Product Name |
Information |
| PC-21999 |
N-chloroacetyltryptamine
AANAT inhibitor
|
N-chloroacetyltryptamine is a potent in vitro and in vivo AANAT acetyltransferase inhibitor with IC50 of 5.2 uM. |
| PC-21998 |
AANAT inhibitor 1
AANAT inhibitor
|
AANAT inhibitor 1 is a highly potent arylalkylamine N-acetyltransferase (AANAT) inhibitor with IC50 of 500 nM, covalently reacts with AANAT product CoASH. |
| PC-21975 |
Canlitinib
|
Canlitinib is a tyrosine kinase inhibitor, extracted from patent WO2018072614 (IV-2). |
| PC-21972 |
Bezisterim
|
Bezisterim (HE3286) is an orally bioavailable synthetic analogue of an active DHEA metabolite, displays both glucose-lowering and cholesterol-lowering effects. |
| PC-21945 |
EBP inhibitor 11
EBP inhibitor
|
EBP inhibitor 11 is a potent, selective, brain-penetrant, orally bioavailable inhibitor of emopamil binding protein (EBP) with mGCMS zymo EC50 of 8 nM, and OPC differentiation EC50 of 44 nM. |
| PC-21942 |
PU.1 inhibitor A11
PU.1 inhibitor
|
PU.1 inhibitor A11 is a small molecule inhibitor of transcription factor PU.1 with EC50 of 2.5 nM in reporter assays, moderates the inflammatory response in human iPSC-derived microglia-like cells (iMGLs) by downregulating inflammatory PU.1-target gene expression without affecting hematopoiesis. |
| PC-21926 |
AZ9567
MAT2A inhibitor
|
AZ9567 is a potent, selective methionine adenosyltransferase 2A (MAT2A) inhibitor with IC50 of 1 nM, selectively targets MTAP-deficient cancer cells. |
| PC-21924 |
MAGMAS inhibitor BT9
MAGMAS inhibitor
|
MAGMAS inhibitor BT9 is a small molecule MAGMAS (mitochondria associated, granulocyte-macrophage colony stimulating factor signaling molecule) inhibitor with binding Kd of 33 uM. |
| PC-21923 |
Epoxykynin
sEH inhibitor
|
Epoxykynin is a potent, selective soluble epoxide hydrolase (sEH) with IC50 of 36 nM, inhibits the hydrolase activity of sEH and modulates kynurenine pathway. |
| PC-21895 |
MAT2A inhibitor 29
MAT2A inhibitor
|
MAT2A inhibitor 29 (AZ-29) is a potent and selective inhibitor of methionine adenosyltransferase MAT2A with IC50 of 27.9 nM. |
| PC-21877 |
AKST1220
LTA4H inhibitor
|
AKST1220 is a potent, specific leukotriene A4 hydrolase (LTA4H) inhibitor, improves hippocampal dependent memory. |
| PC-21871 |
FEN1-IN-4
FEN1 inhibitor
|
FEN1-IN-4 is a specific, competitive inhibitor of human flap endonuclease-1 (hFEN1) with IC50 of 30 nM, binds to atalytic metals and blocks DNA unpairing. |
