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ML257

Chemical Structure : ML257

CAS No.: 1362735-90-7

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ML257 (ABL303)

Catalog No.: PC-22333Not For Human Use, Lab Use Only.

ML257 (ABL303) is a selective inhibitor of α,β-hydrolase domain-containing 10 (ABHD10) with IC50 of 21 nM, >59-fold selectivity over 40+ other serine hydrolases.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ML257 (ABL303) is a selective inhibitor of α,β-hydrolase domain-containing 10 (ABHD10) with IC50 of 21 nM, >59-fold selectivity over 40+ other serine hydrolases.

Physicochemical Properties

M.Wt 362.43
Formula C19H26N2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

diisopropyl (R)-3-ethyl-4-oxo-3-(p-tolyl)-1,2-diazetidine-1,2-dicarboxylate

References

1. Andrea M Zuhl, et al. J Am Chem Soc. 2012 Mar 21;134(11):5068-71.

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