QDPR inhibitor 9b | QDPR inhibitor | Probechem Biochemicals

Chemical Structure : QDPR inhibitor 9b

CAS No.: 29415-71-2

QDPR inhibitor 9b (Compound 9b)

Catalog No.: PC-22340Not For Human Use, Lab Use Only.

QDPR inhibitor 9b is a small molecule inhibitor of quinonoid dihydropteridine reductase (QDPR) with IC50 of 0.72 uM.

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10 mg	$298	In stock
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Biological Activity

QDPR inhibitor 9b is a small molecule inhibitor of quinonoid dihydropteridine reductase (QDPR) with IC50 of 0.72 uM.
Treatment with QDPR inhibitor 9b combined with methotrexate (MTX), an inhibitor of another BH4-reducing enzyme, dihydrofolate reductase (DHFR), significantly oxidized intracellular redox states in HepG2, Jurkat, SH-SY5Y, and PC12D cells.

Physicochemical Properties

M.Wt	233.27
Formula	C12H15N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-(diethylamino)-2,3-dihydrophthalazine-1,4-dione

References

1. Satoshi Hara, et al. Biochem Biophys Res Commun. 2024 May 4:717:150059.

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QDPR inhibitor 9b (Compound 9b)

Biological Activity

Physicochemical Properties

References

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