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Cat. No. Product Name Information
PC-24048

BM-8372

TLT-1 inhibitor

BM-8372 is a potential small molecule inhibitor of TREM-like transcript-1 (TLT-1), inhibits the binding to fibrinogen, demonstrates significant effect in platelet aggregation and spreading assays.
PC-24044

TIX100

TXNIP inhibitor

SRI-37330 (TIX100) is an orally available small molecule that regulates TXNIP expression, inhibits endogenous TXNIP mRNA expression (IC50=0.64 uM, INS-1 cells qRT-PCR assays).
PC-24039

RUN-47

NRF1 activator

RUN-47 is a small-molecule activator of NRF1 with EC50 of 6.43 uM in 3xPSMA4-ARE-LUC reporter assays, specifically activates NRF1 pathway.
PC-24030

Diacerein

IL-1β inhibitor

Diacerein (Diacerhein) is an orally active anthraquinone, reduces production of IL-1 converting enzyme then inhibits the activation of IL-1β by related downstream signaling, also is a highly efficacious inhibitor of main protease (Mpro) of SARS-CoV-2, shows anti-inflammatory and anti-rheumatic effect.
PC-24009

Apigenin

MARK4 inhibitor

Apigenin is a small molecule inhibitor of Microtubule Affinity-Regulating Kinase 4 (MARK4) with IC50 of 2.39 uM, exerts neuroprotective effects.
PC-24008

ST-5-002

TM4SF5 inhibitor

ST-5-002 is a specific small molecule inhibitor of transmembrane 4 L six family member 5 (TM4SF5), inhibits signaling lymphocytic activation molecule family member 7 (SLAMF7) degradation due to TM4SF5 binding and lysosomal translocation.
PC-24006

Dracorhodin

CMPK2 inhibitor

Dracorhodin is the main component in sanguis draconis that can induce vasodilatation, inhibits cytidine/uridine monophosphate kinase 2 (CMPK2) and attenuates inflammation.
PC-23998

GJG057

LTC4S inhibitor

GJG057 is a potent, selective and orally bioavailable inhibitor of leukotriene C4 synthase (LTC4S) with IC50 of 44 nM in whole blood LTC4 release assay and 14 nM in enzymatic assays.
PC-23996

ZYS-1

ADAR1 inhibitor

ZYS-1 is a potent small-molecule ADAR1 (denosine deaminase acting on RNA 1) inhibitor, suppresses PCa growth and metastasis and potentiated the antitumor immune response.
PC-23983

AM-3607

GlyR PAM

AM-3607 is a potent, positive allosteric modulator of mammalian ionotropic glycine receptor (GlyR) subtypes with EC50 of 25 nM (hGlyRα3β), SPR Kd of 11 nM.
PC-23982

AM-1488

GlyR PAM

AM-1488 is a potent, positive allosteric modulator of mammalian ionotropic glycine receptor (GlyR) subtypes with EC50 of 0.45 uM (hGlyRα3β), SPR Kd of 0.19 uM.
PC-23969

BPK-21

ERCC3 inhibitor

BPK-21 is a specific inhibitor of helicase ERCC3, suppresses T cell activation through blockade of ERCC3 function, targets C342 in ERCC3.

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