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Cat. No. Product Name Information
PC-24652

hCES2A inhibitor 9d

hCES2A inhibitor

hCES2A inhibitor 9d is a potent, selective and covalent human carboxylesterase 2A (hCES2A) inhibitor with IC50 of 0.12 nM and Ki of 0.43 nM.
PC-24651

LC-20W

hCES2A inhibitor

LC-20W is potent, reversible human carboxylesterase 2A (hCES2A) inhibitor with IC50 of 1.6 nM.
PC-24650

Cucurbitacin B

IGF2BP1 inhibitor

Cucurbitacin B (CuB) is a potent but toxic anticancer natural product, an irreversible covalent inhibitor of IGF2BP1 and forms a covalent bond with cysteine 253 of the IGF2BP1 KH 1-2 domain (KD=66.8 nM).
PC-24649

IGF2BP1 inhibitor A11

IGF2BP1 inhibitor

IGF2BP1 inhibitor A11 is a specific small molecule insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) inhibitor, binds to IGF2BP) protein with KD of 2.88 nM.
PC-24648

DB2115 tertahydrochloride

PU.1 inhibitor

DB2115 tertahydrochloride is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 1.0 nM.
PC-24627

HSD17B13 inhibitor 32

HSD17B13 inhibitor

HSD17B13 inhibitor 32 is a highly potent, selective and liver-targeting HSD17B13 inhibitor with IC50 of 2.5 nM.
PC-24621

Fis1 inhibitor SP11

Fis1 inhibitor

SP11 is a potent inhibitor of activated Fis1 (mitochondrial fission protein 1), covalently binds specifically to Cys41 of activated Fis1, inhibits CPM fluorescence of Thr34Asp Fis1 with IC50 of 9.4 uM.
PC-24615

Digitonin

Detergent agent

Digitonin is a natural glycoside detergent glycoside obtained from Digitalis purpurea, can increase cell permeability by binding to cholesterol molecules and reduce tumor growth.
PC-24611

CVB4-57

Cx26 hemichannels inhibitor

CVB4-57 is a specific, reversible small molecule Connexin26 hemichannel (Cx26 hemichannel), reversibly inhibited the dye uptake at 5 uM without affecting the gap junction communication and barrier function.
PC-24605

Concanavalin A

Liver injury inducer

Concanavalin A is a Ca2+/Mn2+-dependent and mannose/glucose-binding plant lectin, can induce programmed cell death and acute liver injury.
PC-24596

SALL4 inhibitor SH6

SALL4 degrader

SALL4 inhibitor SH6 is a small molecule inhibitor of transcription factor SALL4 ZFC4 domain, selectively targets SALL4-expressing cancer cells (EC50=0.5 uM, SNU398 cells), degrades SALL4 protein through the CUL4A/CRBN pathway.
PC-24578

TrpGc

HINT1 inhibitor

TrpGc (Tryptamine guanosine carbamate) is a pharmacologically active histidine triad nucleotide-binding protein (HINT1) inhibitor with Kd of 3.65 uM, IC50 of 9.1 uM.

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