| Cat. No. |
Product Name |
Information |
| PC-23352 |
MASTL-IN-1
MASTL inhibitor
|
MASTL-IN-1 is a potent, selective inhibitor of microtubule-associated serine/threonine kinase-like (MASTL, Greatwall) with Ki of 4.4 nM, cellular pENSA IC50 of 23 nM. |
| PC-23351 |
MASTL inhibitor 16
MASTL inhibitor
|
MASTL inhibitor 16 is a potent, highly selective inhibitor of microtubule-associated serine/threonine kinase-like (MASTL, Greatwall) with Ki of 0.12 nM, cellular pENSA IC50 of 2.8 nM in MDA-MB-231 cells. |
| PC-23350 |
MASTL inhibitor 15
MASTL inhibitor
|
MASTL inhibitor 15 is a potent, highly selective inhibitor of microtubule-associated serine/threonine kinase-like (MASTL, Greatwall) with Ki of <0.03 nM, cellular pENSA IC50 of 1.1 nM in MDA-MB-231 cells. |
| PC-23327 |
8-prenylnaringenin
CDCP1 inhibitor
|
8-prenylnaringenin (8PN) is a prenylflavonoid isolated from hop cones Humulus lupulus with cytotoxicity, is a small molecule inhibitor of CUB domain‐containing protein 1 (CDCP1)and reduces CDCP1 protein levels in cancer cells. |
| PC-23326 |
HPA-12
CERT inhibitor
|
HPA-12 is a small molecule inhibitor of ceramide trafficking/ceramide transporter (CERT), inhibits sphingomyelin biosynthesis. |
| PC-23325 |
Stomidazolone
Stomatal differentiation inhibitor
|
Stomidazolone is a doubly-sulfonylated imidazolone that inhibits stomatal differentiation, tightly binds to C-terminal ACT-Like (ACTL) domain of MUTE (Kd=8.9 uM) and perturbs the SCRM-MUTE heterodimerization. |
| PC-23324 |
SIM1
Stomatal opening inhibitor
|
SIM1 is a small molecule inhibitor of stomatal opening, inhibits the light induced stomatal opening of Arabidopsis with IC50 of 44.9 uM, affects stomatal aperture. |
| PC-23308 |
AK-778-XXMU
ID2 inhibitor
|
AK-778-XXMU is a small molecule inhibitor of protein ID2 (inhibitor of DNA binding 2) with SPR KD value of 129 nM. |
| PC-23289 |
C071-0684
CHD1L inhibitor
|
C071-0684 is a potent small molecule inhibitor of CHD1L targeting ATP catalytic activity of chromodomain helicase CHD1L (IC50=17.36 uM, KD=0.5 uM), shows IC50 of 13.0 uM against human HCT116 colorectal cancer cells. |
| PC-23287 |
HKi6
HEG1-KRIT1 inhibitor
|
HKi6 is a specific small-molecule HEG1-KRIT1 inhibitor (IC50=1.5 uM) by competing orthosterically with HEG1 for binding to the KRIT1 FERM domain, elevates KLF4 and KLF2 gene expression and increases Akt phosphorylation. |
| PC-23286 |
HKi2
HEG1-KRIT1 inhibitor
|
HKi2 is a specific small-molecule HEG1-KRIT1 inhibitor (IC50=3.5 uM) by competing orthosterically with HEG1 for binding to the KRIT1 FERM domain, elevates KLF4 and KLF2 gene expression and increases Akt phosphorylation. |
| PC-23282 |
Malabaricone C
Sphingomyelin synthase inhibitor
|
Malabaricone C is a natural sphingomyelin synthase (SMS) inhibitor with IC50 values of 3 uM and 1.5 μM for SMS1 and SMS2, respectively. |
