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Cat. No. Product Name Information
PC-22469

BI-43

Glutaminyl cyclase inhibitor

BI-43 is a potent, selective glutaminyl cyclase inhibitor with IC50 of 12 nM and 40 nM for both sQC and gQC, respectively.
PC-22463

HTRA1 inhibitor 17

HTRA1 inhibitor

HTRA1 inhibitor 17 is a highly potent and selective inhibitor of high temperature requirement A serine peptidase 1 (HTRA1) serine protease with IC50 of 13 nM.
PC-22462

HTRA1 inhibitor 10

HTRA1 inhibitor

HTRA1 inhibitor 10 is a highly potent and selective inhibitor of high temperature requirement A serine peptidase 1 (HTRA1) serine protease with IC50 of 10 nM.
PC-22460

DC-5163

GAPDH inhibitor

DC-5163 is a smal molecule glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor with IC50 of 176.3 nM, inhibits glucose uptake, reduces lactic acid production, selectively inhibits cancer cell proliferation.
PC-22448

CMFT

MIF inhibitor

CMFT is a a small molecule inhibitor of the functional interaction between the transcription factor ICBP90 (a.k.a. UHRF1) and the MIF-794 CATT5-8 promoter microsatellite, inhibits MIF mRNA expression in a -794 CATT5-8 length-dependent manner with an IC50 of 470 nM.
PC-22443

P4B

Cellulose biosynthesis inhibitor

P4B is a small molecule cellulose biosynthesis inhibitor of Arabidopsis (Arabidopsis thaliana) seedling growth.
PC-22442

UCM-13369

NPM1 inhibitor

UCM-13369 is a small molecule inhibitor of nucleophosmin 1 (NPM1), inhibits NPM1 expression, downregulates the pathway associated with mutant NPM1 C+, inhibits tumorsphere growth of CSCs.
PC-22430

LW-216

TrxR1 inhibitor

LW-216 is a novel specific small molecule thioredoxin reductase 1 (TrxR1, TXNRD1) inhibitor directly binds TrxR1 (KD of 8.8 uM in MST assays) and persistently promotes TrxR1 ubiquitination, inhibits TrxR1 expression.
PC-22416

UCF-101

Omi/HtrA2 inhibitor

UCF-101 is a specific inhibitor for the pro-apoptotic protease Omi/HtrA2 with IC50 of 9.5 uM, displays high selectivity over other serine proteases.
PC-22408

DUPA

Drug delivery ligand

DUPA is a small molecule delivery ligand with specificity for prostate-specific membrane antigen (PSMA), commonly used for selectively delivery cytotoxic agents to prostate cancer cells.
PC-22397

UNC9750

IPMK inhibitor

UNC9750 is a potent selective inhibitor of inositol phosphate multikinase (IPMK) with IC50 of 31.6 nM, inhibits human glioblastoma cell growth and selectively decreases cellular InsP5 abundance.
PC-22384

ML281

STK33 inhibitor

ML281 is a potent, selective inhibitor of serine/threonine kinase STK33 with IC50 of 14 nM, >500-fold selective over PKA and AurB.

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