| Cat. No. |
Product Name |
Information |
| PC-23069 |
QC-308
Heme oxygenase inhibitor
|
QC-308 is a potent heme oxygenase (HO) inhibitor witn IC50 of 0.27 uM and 0.46 uM for hHO-1 and hHO-2 respectively. |
| PC-23068 |
Azalanstat
HO-1 inhibitor
|
Azalanstat (RS-21607) is a selective cytochrome P450 enzyme lanosterol 14 alpha-demethylase cytochrome P450 enzyme lanosterol 14 alpha-demethylase (LDM), inhibits heme oxygenase 1 (HO-1, IC50=5.3 uM), shows cholesterol-lowering activity. |
| PC-23067 |
CDD-3290
PSA inhibitor
|
CDD-3290 is a specific small molecule inhibitor of prostate-specific antigen (PSA; KLK3) with Ki of 216 nM. |
| PC-23061 |
Sucantomotide
Immunogenic compound
|
Sucantomotide is a (poly)peptide and Immunogenic compound comprising an epitope of IL13RA2, BIRC5 and/or FOXM1 for prevention and treatment of cancer, by cancer immunotherapy. |
| PC-23054 |
Vamagloxistat sodium salt
Glycolate oxidase inhibitor
|
Vamagloxistat (BBP-711) sodium salt is a small molecule inhibitor of glycolate oxidase (GOX, GO) for primary hyperoxaluria type 1 and recurrent kidney stone formers. |
| PC-23053 |
Vamagloxistat
Glycolate oxidase inhibitor
|
Vamagloxistat (BBP-711) is a small molecule inhibitor of glycolate oxidase (GOX, GO) for primary hyperoxaluria type 1 and recurrent kidney stone formers. |
| PC-23045 |
EN300
GPRC6A agonist
|
EN300 is a small ligand agonist for GPRC6A, stimulates ERK phosphorylation and cAMP accumulation with EC50 of 2.331 and 3.448 mM, respectively. |
| PC-23025 |
GSDMD agonist DMB
Gasdermin D agonist
|
GSDMD agonist DMB is a direct and selective gasdermin D (GSDMD) agonist, activates GSDMD pore formation to trigger liposome leakage with EC50 of 0.7 uM, activates GSDMD pore formation and pyroptosis without cleaving GSDMD. |
| PC-23021 |
SRSF10 inhibitor 1C8
SRSF10 inhibitor
|
SRSF10 inhibitor 1C8 is a specific small molecule inhibitor of SRSF1, alters splicing regulation mediated by SRSF10, shows strong anti-HIV-1 potency against a variety of clinical strains in vitro. |
| PC-23018 |
Aulosirazole
FOXO3a modulator
|
Aulosirazole, an isothiazolonaphthoquinone alkaloid, shows cytotoxic activity against OVCAR3 cells (IC50=301 nM), promotes forkhead box O3a (FOXO3a) nuclear accumulation and modulates downstream targets. |
| PC-22980 |
Peptide SBT-20
ROS-lowering peptide
|
Peptide SBT-20 (SS-20) is a cell-permeable peptide targeting the inner mitochondrial membrane, reduces ROS, normalizes electron transport chain function and ATP generation. |
| PC-22978 |
Peptide NAPLVHATL
KIR2DS2 ligand
|
Peptide NAPLVHATL is an XPO1-derived peptide and a ligand for KIR2DS2, can be recognized by the activating NK cell receptor KIR2DS2 in the context of human leukocyte antigen-C. |
