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Cat. No. Product Name Information
PC-23825

BSc5367

Nek1 inhibitor

BSc5367 is a potent, selective inhibitor of NIMA-related protein kinase Nek1 (NimA related kinase 1) with IC50 of 11.5 nM.
PC-23824

Paquinimod

S100A9 inhibitor

Paquinimod (ABR-215757) is a specific inhibitor of S100A9, inhibits S100A8/S100A9 binding to RAGE, reduces diabetes-induced thrombocytosis.
PC-23822

Butylphthalide

6066-49-5

Butylphthalide (3-n-Butylphthalide, NBP) is an active molecule against cerebral ischemia, shows neuroprotective activity for acute ischemic stroke.
PC-23814

Cefcapene pivoxil hydrochloride hydrate

GSDMD inhibitor

Cefcapene pivoxil hydrochloride hydrate (Compound 98) is an orally active third-generation cephalosporin with a wide spectrum of anti-bacterial activity, also is a specific small molecule inhibitor of gasdermin D (GSDMD) targeting the GSDMD N-terminal oligomerization interface I (MST KD=0. 32uM), exert pyroptosis inhibitory effects.
PC-23813

SCR-1481B1

GSDMD inhibitor

SCR-1481B1 (Metatinib anhydrous, Compound 68) is a specific small molecule inhibitor of gasdermin D (GSDMD) targeting the GSDMD N-terminal oligomerization interface I (MST KD=0.4 uM), exert pyroptosis inhibitory effects, also shows inhibition on Met activation VEGFR.
PC-23808

ARC39

Acid sphingomyelinase inhibior

ARC39 is a direct, selective acid sphingomyelinase (ASM) inhibitor with IO50 of 20 nM, inhibits both lysosomal and secretory ASM in vitro.
PC-23800

LFHP-1c

PGAM5 inhibitor

LFHP-1c is a direct phosphoglycerate mutase family member 5 (PGAM5) inhibitor with binding SPR KD of 961 nM, not only inhibits the PGAM5 phosphatase activity, but also reduces the interaction of PGAM5 with NRF2.
PC-23794

KKT3054

KAI2 antagonist

KK181N1 is a specific inhibitor of karrikins (KARs) receptor KAI2, selectively inhibits Arabidopsis karrikin signaling, binds to the catalytic pocket of AtKAI2 with Kd of 14.9 uM.
PC-23793

KK181N1

KAI2 antagonist

KK181N1 is a specific inhibitor of karrikins (KARs) receptor KAI2, selectively depresses the KAR-induced phenotypes in Arabidopsis, binds to the catalytic pocket of AtKAI2 with Kd of 27.7 uM.
PC-23789

PQ529

QC/isoQC inhibitor

PQ529 is a selective glutaminyl cyclase (QC, QPCT) / isoenzyme of glutaminyl cyclase (isoQC, QPCTL) inhibitor.
PC-23787

PFKFB2 inhibitor B2

PFKFB2 inhibitor

PFKFB2 inhibitor B2 is a small molecule inhibitor of PFKFB2 (6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 2) with IC50 of 3.29 uM, inhibits PFKFB3 with IC50 of 11.89 uM.
PC-23783

BL001

LRH-1 agonist

BL001 is a specific small molecule agonist of liver receptor homologue-1 (LRH-1) with EC50 of 0.1 uM, specifically binds to and activates LRH-1.

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