| Cat. No. |
Product Name |
Information |
| PC-42293 |
EC330
LIF inhibitor
|
EC330 (EC-330, EC 330) is a first-in-class, orally bioavailable LIF (leukemia inhibitory factor) inhibitor. |
| PC-45088 |
SP-420
Iron chelating agent
|
Petadeferitrin (SP-420) is a desferrithiocin analogue and iron chelating agent that has iron-clearing efficiency with ICE value of 26.7, SP-420 is more potent than desferrithiocin. |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-25712 |
RWT9996
GPR17 antagonist
|
RWT9996 is a potent, selective GPR17 antagonist, inhibits both G protein activation and β-arrestin-2 recruitment. |
| PC-25706 |
hCES2A inhibitor C3
hCES2A inhibitor
|
hCES2A inhibitor C3 is a highly potent, orally active and serine-targeting covalent inhibitor of hCES2A (human carboxylesterase 2A) with IC50 of 0.56 nM, Ki of 1.58 nM. |
| PC-25702 |
ARN14686
NAAA probe
|
ARN14686 is a click chemistry activity-based probe (CC-ABP) that selectively recognizes the enzyme N-acylethanolamine acid amidase (NAAA). |
| PC-25694 |
Auxurea A
GH3 inhibitor
|
Auxurea A is a selective competitive small molecule inhibitor of IAA-amino acid conjugating enzymes GH3, specifically inhibited GH3-mediated IAA inactivation both in vivo and in vitro, induces high-auxin phenotypes in Arabidopsis. |
| PC-25661 |
TDRL-505
RPA inhibitor
|
TDRL-505 is a small molecule inhibitor of Replication protein A (RPA) with IC50 of 13 uM, inhibits RPA's DNA binding activity targeting DBD-A and B in the 70 kDa subunit of RPA. |
| PC-25635 |
TTZ-2
zDHHC2 inhibitor
|
TTZ-2 (zDHHC2 inhibitor TTZ2) is a specific enzymatic inhibitor of ZDHHC2, inhibits human zDHHC2-mediated substrate (SNAP25) S-acylation in vitro with IC50 of 1.3 uM. |
