| Cat. No. |
Product Name |
Information |
| PC-45088 |
SP-420
Iron chelating agent
|
Petadeferitrin (SP-420) is a desferrithiocin analogue and iron chelating agent that has iron-clearing efficiency with ICE value of 26.7, SP-420 is more potent than desferrithiocin. |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-25942 |
TREM-1 inhibitory peptide GF9
TREM-1 inhibitor
|
TREM-1 inhibitory peptide GF9 is a peptide inhibitor of Triggering receptor expressed on myeloid cells 1 (TREM-1), significantly inhibits pancreatic cancer progression. |
| PC-25930 |
GPR81 agonist 1
GPR81 agonist, HCAR1 agonist
|
GPR81 agonist 1 is a potent and highly selective GPR81 agonist with EC50 of 58 nM and 50 nM for human and mouse GPR81 respectively, also is an agonist-positive allosteric modulator (Ago-PAM) for HCAR1. |
| PC-25903 |
2-Bromopalmitate
Palmitoylation inhibitor
|
2-Bromopalmitate (2-Bromohexadecanoic acid, 2-Bromopalmitic acid) is a broad-spectrum palmitoylation inhibitor, inhibits ZDHHC11-mediated palmitoylation, inhibits palmitoylation of GSDME-C during pyroptosis and inhibits BAK/BAX-Caspase 3-GSDME pathway-mediated pyroptosis. |
| PC-25886 |
Them1 inhibitor Compound U11
Them1 inhibitor
|
Them1 inhibitor Compound U11 is a small molecule inhibitor of thioesterase superfamily member 1 (Them1) with IC50 of 3.63 uM, selectively inhibits Them1 by binding the START domain (Kd=0.67 uM). |
| PC-25885 |
Them1 inhibitor Compound U1
Them1 inhibitor
|
Them1 inhibitor Compound U1 is a small molecule inhibitor of thioesterase superfamily member 1 (Them1) with IC50 of 8.64 uM, selectively inhibits Them1 by binding the START domain (Kd=5.97 uM). |
| PC-25882 |
PPTD free base
ZIP14 inhibitor
|
PPTD free base is the first selective small-molecule inhibitor of membrane-bound metal transporter ZIP14/SLC39A14, efficiently blocks ZIP14-mediated uptake of zinc, iron, manganese and cadmium, while sparing the closely related transporter ZIP8/SLC39A8. |
| PC-25881 |
ZIP14 inhibitor PPTD
ZIP14 inhibitor
|
ZIP14 inhibitor PPTD is the first selective small-molecule inhibitor of membrane-bound metal transporter ZIP14/SLC39A14, efficiently blocks ZIP14-mediated uptake of zinc, iron, manganese and cadmium, while sparing the closely related transporter ZIP8/SLC39A8. |
