BMS-354326 | Tryptase inhibitor | Probechem Biochemicals

Chemical Structure : BMS-354326

BMS-354326 (BMS354326)

Catalog No.: PC-25176Not For Human Use, Lab Use Only.

BMS-354326 is a highly potent, selective tryptase inhibitor with IC50 of 1.8 nM, shows excellent selectivity against trypsin and most other related serine proteases.

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Biological Activity

BMS-354326 is a highly potent, selective tryptase inhibitor with IC50 of 1.8 nM, shows excellent selectivity against trypsin and most other related serine proteases.
BMS-354326 is over 5000-fold selective against trypsin.

Physicochemical Properties

M.Wt	512.65
Formula	C28H40N4O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,3R)-4-oxo-1-(4-(6-phenylhexanoyl)piperazine-1-carbonyl)-3-(2-(piperidin-3-yl)ethyl)azetidine-2-carboxylic acid

References

1. Bisacchi GS, et al. Bioorg Med Chem Lett. 2004 May 3;14(9):2227-31.

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BMS-354326 (BMS354326)

Biological Activity

Physicochemical Properties

References

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