| Cat. No. |
Product Name |
Information |
| PC-38779 |
LCL521
Acid ceramidase inhibitor
|
LCL521 is a small molecular inhibitor of acid ceramidase (ACDase), a lysosomotropic inhibitor with anticancer activity. |
| PC-38777 |
STK793590
DJ-1/PARK7 inhibitor
|
STK793590 (DJ-1/PARK7 inhibitor 15) is a potent inhibitor of the Parkinson's disease associated protein DJ-1/PARK7 with Kd/IC50 of 0.1/0.28 uM, respectively. |
| PC-38774 |
PXS-5505
pan-LOX inhibitor
|
Amsulostat (PXS-5505) is an orally available, small-molecule, irreversible inhibitor of all lysyl oxidases (pan-LOX) family members, with potential antifibrotic activity. |
| PC-38773 |
LSALT peptide
DPEP-1 inhibitor
|
Metablok (LSALT peptide) is a specific DPEP1-binding peptide and nonenzymatic dipeptidase-1 (DPEP-1) inhibitor. |
| PC-38767 |
S202
Ceramide galactosyltransferase inhibitor
|
S202 is a potent, selective and brain-penetrant small molecule inhibitor of ceramide galactosyltransferase (CGT) with IC50 of 15 nM in the cell-lysate assays and 3.6 nM in intact-cell assays. |
| PC-38755 |
CT-179
OLIG2 inhibitor
|
CT-179 is a small molecule inhibitor of protein transcription factor OLIG2 (Oligodendrocyte transcription factor 2), CT-179 is a putative disruptor of OLIG2 homodimerization. |
| PC-38753 |
PAT1inh-B01
SLC26A6 (PAT1) inhibitor
|
PAT1inh-B01 is a small-molecule, selective SLC26A6 (putative anion transporter 1, PAT1) inhibitor, could fully inhibit PAT1-mediated anion exchange with IC50 of 350 nM. |
| PC-38737 |
CQ211
RIOK2 inhibitor
|
CQ211 is a potent, highly selective RIOK2 (Right open reading frame kinase 2) inhibitor with Kd of 6.1 nM, shows excellent selectivity to RIOK2 in both enzymatic and cellular assays. |
| PC-38736 |
DX3-213B
OXPHOS inhibitor
|
DX3-213B is a potent oxidative phosphorylation (OXPHOS) complex I inhibitor with IC50 of 3.6 nM, inhibits pancreatic cancer cells growth in the low nanomolar range (MIA PaCa-2, GI50=11 nM). |
| PC-38722 |
GO-Y078
Angiogenesis inhibitor
|
GO‐Y078 is a curcumin analog that suppresses angiogenesis through the inhibition of actin stress fiber formation, inhibits human umbilical venous epithelial cells resistant to angiogenesis inhibitors (HUVEC‐R) at 0.75 uM. |
| PC-38711 |
TFF3 inhibitor AMPC
TFF3 inhibitor
|
AMPC is a first-in-class small-molecule inhibitor of the oncogenic functions of trefoil factor 3 (TFF3) that specifically monomerizes dimeric TFF3 to inhibit dimeric TFF3 function, specifically binds to Cys57 of TFF3. |
| PC-38705 |
AF615
CDT1/Geminin inhibitor
|
AF615 is a potent and selective small-molecule inhibitor targeting the CDT1/Geminin protein complex with Ki of 0.37 uM aginst Geminin-tCDT1 interaction, inhibits inhibit Geminin/CDT1 complex formation in vitro with IC50 of 0.313 uM. |
