| Cat. No. |
Product Name |
Information |
| PC-38904 |
CIB-3b
TRBP-Dicer inhibitor
|
CIB-3b is a small molecule inhibitor disrupting the TRBP-Dicer interaction, suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells. |
| PC-38900 |
XST-20
FOXM1 inhibitor
|
XST-20 is a small molecule selectively targeting FOXM1 DNA-binding domain (DBD) with SPR Kd of 20 uM, effectively suppresses FOXM1 transcriptional activities and inhibits ovarian cancer cell proliferation. |
| PC-38889 |
Alrefimotide
|
Alrefimotide (Telomerase reverse transcriptase 660-689 peptide antigen). |
| PC-38841 |
UK5099
MPC blocker
|
UK5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier (MPC), inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria with IC50 of 50 nM. |
| PC-38797 |
ERX-41
LIPA inhibitor
|
ERX-41 is a small molecule that binds to lysosomal acid lipase A (LIPA), and induces endoplasmic reticulum (ER) stress resulting in cell death, blocks proliferation of ER-α⁺ BC cells and TNBC cells in vitro. |
| PC-38788 |
Sarcomere inhibitor W7
Sarcomere inhibitor
|
Sarcomere inhibitor W7 is a small-molecule sarcomere Ca2+ desensitizer, decreases intact cardiac myocyte contractility in a Ca2+ transient amplitude-independent manner. |
| PC-38785 |
EVT-701
Mitochondrial complex 1 inhibitor
|
EVT-701 is a highly potent, selective, and safe mitochondrial complex 1 (MC1) inhibitor, reduces NADH abundance with IC50 of 300 nM. |
| PC-38779 |
LCL521
Acid ceramidase inhibitor
|
LCL521 is a small molecular inhibitor of acid ceramidase (ACDase), a lysosomotropic inhibitor with anticancer activity. |
| PC-38777 |
STK793590
DJ-1/PARK7 inhibitor
|
STK793590 (DJ-1/PARK7 inhibitor 15) is a potent inhibitor of the Parkinson's disease associated protein DJ-1/PARK7 with Kd/IC50 of 0.1/0.28 uM, respectively. |
| PC-38774 |
PXS-5505
pan-LOX inhibitor
|
Amsulostat (PXS-5505) is an orally available, small-molecule, irreversible inhibitor of all lysyl oxidases (pan-LOX) family members, with potential antifibrotic activity. |
| PC-38773 |
LSALT peptide
DPEP-1 inhibitor
|
Metablok (LSALT peptide) is a specific DPEP1-binding peptide and nonenzymatic dipeptidase-1 (DPEP-1) inhibitor. |
| PC-38767 |
S202
Ceramide galactosyltransferase inhibitor
|
S202 is a potent, selective and brain-penetrant small molecule inhibitor of ceramide galactosyltransferase (CGT) with IC50 of 15 nM in the cell-lysate assays and 3.6 nM in intact-cell assays. |
