| Cat. No. |
Product Name |
Information |
| PC-38607 |
ML145
GPR35 inhibitor
|
ML145 (CID-2286812) is a selective GPR35 antagonist with IC50 of 20.1 nM, >1000-fold selectivity over GPR55. |
| PC-38606 |
CID 2745687
GPR35 inhibitor
|
CID-2745687 is a potent, selective and competitive GPR35 antagonist with pIC50 of 6.7 against human GPR35. |
| PC-38605 |
FPPS-IN-11
FPPS inhibitor
|
FPPS-IN-11 is a potent, allosteric, non-bisphosphonate farnesyl pyrophosphate synthase (FPPS) inhibitor with IC50 of 200 nM. |
| PC-38601 |
VK-28
Iron chelator
|
VK-28 is a novel brain permeable neuroprotective iron chelator with anti-Alzheimer's disease activities, inhibits both basal and Fe/ascorbate-induced mitochondrial membrane lipid peroxidation with IC50 of 12.7 uM. |
| PC-38593 |
Synucleozid hydrochloride
α-synuclein inhibitor
|
Synucleozid hydrochloride (NSC 377363) is a small molecule that targets the IRE structure and inhibits SNCA gene translation in cells, directly targets the α-synuclein mRNA 5'UTR at the designed site. |
| PC-38581 |
HyT36
Hydrophobic tag
|
HyT36 is a small-molecule hydrophobic tag compound for the degradation of stabilized proteins, induces an acute, resolvable ER stress that results in transient UPR activation without induction of apoptosis in ERHT-expressing cells. |
| PC-38576 |
ElteN378
FKBP12 inhibitor
|
ElteN378 is a highly potent synthetic inhibitor of FKBP12 with Ki of 0.5 nM, a low atomic weight ligand with affinity comparable to that of the macrolide Rapamycin |
| PC-38564 |
PKN3 inhibitor 16
PKN3 inhibitor
|
PKN3 inhibitor 16 is a potent, cell active protein kinase novel 3 (PKN3) inhibitor with biochemical IC50 of 14 nM, celluar IC50 of 1.3 uM. |
| PC-38552 |
EC23
|
EC23 (AGN190205) is a photostable synthetic retinoid and analog of ATRA, potently induces neural differentiation in human pluripotent embryonic stem cells. |
| PC-38546 |
DL5H3
|
DL5H3 is a bioactive compound with antiasthmatic activity. |
| PC-38539 |
KLH45
DDHD2 inhibitor
|
KLH45 is a potent, selective and in vivo-active serine hydrolase DDHD2 inhibitor with IC50 of 1.3 nM, shows excellent selectivity against other serine hydrolases with exception of ABHD6. |
| PC-38530 |
NCGC607
GCase activator
|
NCGC00241607 (NCGC607) is a small-molecule noninhibitory chaperone of glucocerebrosidase (GCase), successfully chaperoned the mutant enzyme, restored GCase activity and protein levels, and reduced glycolipid storage in neurons. |
