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MCI-100

Chemical Structure : MCI-100

CAS No.: 1945942-59-5

MCI-100 (MCI100, MCI 100)

Catalog No.: PC-49090Not For Human Use, Lab Use Only.

MCI-100 is a small molecule that displays greater potency than sulindac to protect RPE cells against oxidative damage, with lacked significant COX inhibitory activity, MCI-100 is more active than sulindac in protecting cells against oxidative damage.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MCI-100 is a small molecule that displays greater potency than sulindac to protect RPE cells against oxidative damage, with lacked significant COX inhibitory activity, MCI-100 is more active than sulindac in protecting cells against oxidative damage.
    MCI-100 also protected the intact rat heart against ischemia/reperfusion damage following oral administration.

    Physicochemical Properties

    M.Wt 426.465
    Formula C24H26O7
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (Z)-2-(5,6-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzylidene)-1H-inden-3-yl)acetic acid

    References

    1. Allani SK, et al. J Pharmacol Exp Ther. 2022 Jun 9:JPET-AR-2022-001086.

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