| Cat. No. |
Product Name |
Information |
| PC-47485 |
Neuromedin N
|
A neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.. |
| PC-44669 |
Lucidin
|
Lucidin (NSC 30546) is a mutagenic substance extracted from Rubia tinctorum L., induces DNA repair synthesis in primary rat hepatocytes and transformed C3H/M2-mouse fibroblasts in culture. |
| PC-42293 |
EC330
LIF inhibitor
|
EC330 (EC-330, EC 330) is a first-in-class, orally bioavailable LIF (leukemia inhibitory factor) inhibitor. |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-23649 |
Genipin
UCP2 inhibitor
|
Genipin is a specific small molecule inhibitor of uncoupling protein 2 (UCP2), inhibits UCP2-mediated mitochondrial proton leak. |
| PC-23640 |
cGAS inhibitor 36
cGAS inhibitor
|
cGAS inhibitor 36 is a potent, orally bioavailable inhibitor of cyclic GMP-AMP synthase (cGAS) with biochemical IC50 of 32 nM and 5.8 nM for h-cGAS and m-cGAS respectively. |
| PC-23604 |
CCG257081
MRTF/SRF inhibitor
|
CCG-257081 is a small molecule MRTF/SRF pathway inhibitor, shows direct binding to pirin with ITC KD value of 8.6 uM, inhibits melanoma metastasis and bleomycin-induced fibrosis. |
| PC-23586 |
NB-598
Squalene epoxidase inhibitor
|
NB-598 (NB598) is a potent competitive inhibitor of squalene epoxidase (SQLE, SE, squalene monooxygenase) with IC50 of 4.4 nM (rat SE), inhibits microsomal squalene epoxidase from dog liver and Hep G2 cells with IC50 of 2.0 and 0.75 nM, respectively. |
| PC-23580 |
Licochalcone C
α-glycosidase inhibitor
|
Licochalcone C is a selective inhibitor of α-glycosidase with IC50 of <100 nM, does not inhibit PTP1B, induces apoptosis via Bcl-2 family proteins in T24 cells. |
