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Mizoribine

Chemical Structure : Mizoribine

CAS No.: 50924-49-7

Mizoribine (NSC289637, HE-69)

Catalog No.: PC-45288Not For Human Use, Lab Use Only.

Mizoribine (NSC289637, HE-69) is an immunosuppressive agent that inhibits the proliferation of lymphocytes selectively, via inhibition of IMPDH, also inhibits HCV RNA replication with IC50 of 100 uM, inhibits replication of SARS-CoV.

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Biological Activity

Mizoribine (NSC289637, HE-69) is an immunosuppressive agent that inhibits the proliferation of lymphocytes selectively, via inhibition of IMPDH, also  inhibits HCV RNA replication with IC50 of 100 uM, inhibits replication of SARS-CoV.

Physicochemical Properties

M.Wt 259.216
Formula C9H13N3O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 35 mg/mL

Chemical Name/SMILES

1H-Imidazole-4-carboxamide, 5-hydroxy-1-β-D-ribofuranosyl-

References

1. Naka K, et al. Biochem Biophys Res Commun. 2005 May 13;330(3):871-9.
2. Saijo M, et al. Antiviral Res. 2005 Jun;66(2-3):159-63.

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