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BAMB-4

Chemical Structure : BAMB-4

CAS No.: 891025-25-5

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BAMB-4 (ITPKA-IN-C14)

Catalog No.: PC-45040Not For Human Use, Lab Use Only.

BAMB-4 is a specific and membrane-permeable inhibitor of the InsP3Kinase activity of ITPKA (inositol-1,4,5-trisphosphate-3-kinase A) with IC50 of 20 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BAMB-4 is a specific and membrane-permeable inhibitor of the InsP3Kinase activity of ITPKA (inositol-1,4,5-trisphosphate-3-kinase A) with IC50 of 20 uM.
BAMB-4 shows an inhibitory effect only in one from 42 targets tested.
BAMB-4 is a promising therapeutic approach in lung cancer therapy.

Physicochemical Properties

M.Wt 252.268
Formula C15H12N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 40 mg/mL
Chemical Name/SMILES

Benzamide, N-1,2-benzisoxazol-3-yl-4-methyl-

References

1. Schröder D, et al. Biochem Biophys Res Commun. 2013 Sep 20;439(2):228-34.

2. Schröder D, et al. Biochem Pharmacol. 2015 Jul 15;96(2):143-50.

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