| Cat. No. |
Product Name |
Information |
| PC-72298 |
CBX6 inhibitor 5
CBX6 inhibitor
|
CBX6 inhibitor 5 is a selective inhibitor of methyllysine reader protein CBX6 with Kd of 0.9 uM, 90×, 20×, 18×, 6×, and 7× selective for CBX6 over CBX1/2/4/7/8, respectively. |
| PC-72285 |
TH-3021
AKR1C3 inhibitor
|
TH-3021 (SN336384) is a potent and specific inhibitor of AKR1C3 with IC50 of 110 nM in isolated enzyme assays and 18 nM in cellular assays, displays no inhibitory action against AKR1C1/1C2/1C4 (IC50>30 uM). |
| PC-72270 |
SHR170008
CD73 inhibitor
|
SHR170008 is a highly potent, small molecule CD73 inhibitor with IC50 of 0.05 nM against human CD73 soluble enzyme. |
| PC-72241 |
CBLC000
FACT inhibitor
|
CBLC000 (CBL0100) is a small molecule histone chaperone FACT inhibitor, activates p53 and inhibits NF-κB with EC50 of 0.06 and 0.03 uM in cell-based p53 and NF-κB reporter assays, respecitvely. |
| PC-72237 |
Myricetin
ENPP1 inhibitor
|
Myricetin (Myricetol, Myricitin) is a flavonoid compound with antioxidant properties, inhibits ENPP1 enzymatic activity with IC50 of 4.8 uM. |
| PC-72235 |
ENPP1 inhibitor QS1
ENPP1 inhibitor
|
ENPP1 inhibitor QS1 (QPS1) is a potent, selective non-competitive inhibitor of Ectonucleotide pyrophosphatase/PDE1 (NPP1, ENPP1) with Ki of 59.3 nM.
QPS1 also significantly inhibited the K121Q NPP1 gene variant with Ki of 59.2 nM. |
| PC-72175 |
OXS007417
AML differentiation inducer
|
OXS007417 (OXS 007417) is a small moelcule that induces differentiation of AML cells in vitro (CD11b increasein HL-60 cell EC50=48 nM) and shows antitumor effects in vivo. |
| PC-72155 |
L-Propargylglycine
CSE inhibitor
|
L-Propargylglycine (L-PAG) is the most commonly used, covalently irreversible inhibitor inhibitor of cystathionine γ-lyase (CSE). |
| PC-72154 |
CSE inhibitor 43
CSE inhibitor
|
CSE inhibitor 43 is a novel potent, selective, competitive inhibitor of cystathionine γ-lyase (CSE) inhibitor with IC50 of 1.2 uM. |
| PC-72138 |
NSC 773097
|
NSC 773097 is a RITA analog that produces hyperselective cytotoxicity while maintaining antitumor efficacy (A498 cell IC50=130 nM). |
| PC-72132 |
BD50265
GPR52 agonist
|
BD50265 (BD 50265) is a potent small-molecule GPR52 agonist. |
| PC-72131 |
BD442618
GPR52 agonist
|
BD442618 (BD 442618) is a potent small-molecule GPR52 agonist. |
