| Cat. No. |
Product Name |
Information |
| PC-22792 |
TTBK1 inhibitor 31
TTBK inhibitor
|
TTBK1 inhibitor 31 is a potent, selective and CNS-penetrant Tau Tubulin Kinase 1 (TTBK1) inhibitor with IC50 of 2.7 nM, inhibits tau phosphorylation at the disease-relevant Ser 422 epitope. |
| PC-22766 |
Pertussis Toxin
Gi protein inhibitor
|
Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, inhibits G protein-coupled receptor (GPR) signaling through Gi proteins. |
| PC-22760 |
AS1411
Nucleolin inhibitor
|
AS1411 is a quadruplex-forming oligonucleotide aptamer that targets nucleolin, inhibits cancer cell proliferation. |
| PC-22755 |
GCS-12
NKT cell agonist
|
GCS-12 is a highly potent αGalCer sulfonamide analogue as natural killer T (NKT) cell agonist, enhances interaction of the glycolipid/CD1d complex, exhibits selectivity for the induction of IFN-γ over IL-4, shows potent antitumor activities. |
| PC-22754 |
GCS-11
NKT cell agonist
|
GCS-11 is a highly potent αGalCer sulfonamide analogue as natural killer T (NKT) cell agonist, enhances interaction of the glycolipid/CD1d complex, exhibits selectivity for the induction of IFN-γ over IL-4, shows potent antitumor activities. |
| PC-22713 |
Bongkrekic acid
Mitochondrial toxin
|
Bongkrekic acid is a specific small molecule inhibitor of the adenine nucleotide translocase of mitochondria and mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans, inhibits ADP/ATP transport. |
| PC-22708 |
Necrox-7
HMGB1 inhibitor, Necrosis inhibitor
|
NecroX-7 (NecX, NecroX 7) is a small molecule necrosis inhibitor by inhibiting high-mobility group box 1 protein (HMGB1) release. |
| PC-22695 |
LH1753
L-cystine crystallization inhibitor
|
LH1753 is an orally bioavailable inhibitor of L-cystine crystallization for cystinuria, prevents stone formation effectively in the Slc3a1-knockout mouse model. |
| PC-22694 |
DS21360717
FER kinase inhibitor
|
DS21360717 is a highly potent inhibitor of feline sarcoma-related (FER) tyrosine kinase tyrosine kinase with IC50 of 0.49 nM, shows in vivo antitumor efficacy. |
| PC-22693 |
DS08701581
FER kinase inhibitor
|
DS08701581 is a highly potent inhibitor of feline sarcoma-related (FER) tyrosine kinase with IC50 of 0.32 nM, shows in vivo antitumor efficacy. |
| PC-22686 |
NSI-189 phosphate
Neurogenic compound
|
NSI-189 phosphate is an orally active benzylpiperizine-aminiopyridine compound with neurogenic activity, stimulates neurogenesis of human hippocampus-derived neural stem cells in vitro and stimulates neurogenesis in murine hippocampus in vivo. |
| PC-22685 |
NSI-189
Neurogenic compound
|
NSI-189 is an orally active benzylpiperizine-aminiopyridine compound with neurogenic activity, stimulates neurogenesis of human hippocampus-derived neural stem cells in vitro and stimulates neurogenesis in murine hippocampus in vivo. |
