Catalog No.: PC-61994Not For Human Use, Lab Use Only.
TK216 is a first in class, small molecule that directly binds EWS-FLI1 inhibiting the biological activity of ETS-family transcription factor oncoproteins and is currently under clinical investigation against Ewing sarcoma..
TK216 is a first in class, small molecule that directly binds EWS-FLI1 inhibiting the biological activity of ETS-family transcription factor oncoproteins and is currently under clinical investigation against Ewing sarcoma.
TK216 acts as an microtubule destabilizing agent, exhibits anti-cancer activity against cancer cell lines and xenografts that do not express EWSR1-FLI1.
