FQI2 | LSF inhibitor | Probechem Biochemicals

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Chemical Structure : FQI2

FQI2 (FQI 2)

Catalog No.: PC-62025Not For Human Use, Lab Use Only.

FQI2 is a small-molecule inhibitor of transcription factor LSF with IC50 of 0.71 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

FQI2 is a small-molecule inhibitor of transcription factor LSF with IC50 of 0.71 uM.
FQI2 inhibits LSF DNA-binding activity both in vitro, also exhibits antiproliferative activity in multiple cell lines, NIH 3T3, HeLa S3, and A549 cells with GI50 of 0.71, 0.40, and 1.6 uM, respectively.
FQI2 rapidly induces cell death in QGY-7703 liver cancer cell lines.

Physicochemical Properties

M.Wt	309.321
Formula	C18H15NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-(2-ethoxyphenyl)-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one

References

1. Trevor J Grant, et al. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4503-8.

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FQI2 (FQI 2)

Biological Activity

Physicochemical Properties

References

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