Chemical Structure : Trofinetide
CAS No.: 853400-76-7
Catalog No.: PC-61796Not For Human Use, Lab Use Only.
Trofinetide (NNZ 2566) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration.
Packing | Price | Stock | Quantity |
---|---|---|---|
5 mg | $138 | In stock | |
10 mg | $228 | In stock | |
25 mg | $378 | In stock | |
50 mg | $588 | In stock | |
100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Trofinetide (NNZ 2566) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration.
Trofinetide (NNZ 2566) improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury.
Trofinetide (NNZ 2566) significantly reduces injury-mediated up-regulation of IL-1beta, TNF-alpha, E-selectin and IL-6 mRNA in the injured brain in rats.
M.Wt | 315.322 | |
Formula | C13H21N3O6 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
((S)-1-glycyl-2-methylpyrrolidine-2-carbonyl)-L-glutamic acid |
1. Bickerdike MJ, et al. J Neurol Sci. 2009 Mar 15;278(1-2):85-90.
2. Lu XC, et al. J Cereb Blood Flow Metab. 2009 Dec;29(12):1924-32.
3. Wei HH, et al. J Neuroinflammation. 2009 Aug 5;6:19.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright