| Cat. No. |
Product Name |
Information |
| PC-20703 |
IOI-42
hPEBP4 inhibitor
|
hPEBP4 inhibitor IOI-42 is a small molecule inhibitor of anti-apoptotic protein hPEBP4, potentiates TNF-α-mediated growth inhibition of MCF-7 breast cancer cells. |
| PC-20670 |
M3913
WFS1 inhibitor
|
M3913 is a potential, first-in-class WFS1 transmembrane glycoprotein-targeting unfolded protein response (UPR) inducer (ER stress modulator) with EC50 of 1.5 uM for CHOP induction in vitro. |
| PC-20613 |
Perforin inhibitor 3
Perforin inhibitor
|
Perforin inhibitor 3 is a small molecule Perforin inhibitor, inhibits perforin-induced lysis of Jurkat T-lymphoma cells with IC50 of 0.78 uM. |
| PC-20612 |
Perforin inhibitor 2
Perforin inhibitor
|
Perforin inhibitor 2 is a small molecule Perforin inhibitor, inhibits perforin-induced lysis of Jurkat T-lymphoma cells with IC50 of 1.19 uM. |
| PC-20611 |
Perforin inhibitor 1
Perforin inhibitor
|
Perforin inhibitor 1 is a small molecule Perforin inhibitor, inhibits perforin-induced lysis of Jurkat T-lymphoma cells with IC50 of 2.3 uM. |
| PC-20610 |
Perforin inhibitor 5
Perforin inhibitor
|
Perforin inhibitor 5 is a small molecule Perforin inhibitor, inhibits perforin-induced lysis of Jurkat T-lymphoma cells with IC50 of 1.17 uM. |
| PC-20569 |
ERAD inhibitor CP26
Dislocation inhibitor
|
ERAD inhibitor CP26 (NSC26112) is a small molecule inhibitor of Hrd1 complex-mediated dislocation, inhibits NHK dislocation in HeLa cells with IC50 of 4.45 μM in the drGFP assays, shows broad-spectrum anti-flavivirus activity. |
| PC-49726 |
Seletracetam
SV2A ligand
|
Seletracetam (ucb 44212) is a high affinity for the synaptic vesicle protein 2A (SV2A) than levetiracetam with 10-fold, exhibits anticonvulsant properties in animal models of epilepsy. |
| PC-49471 |
MO-I-1100
ASPH inhibitor
|
MO-I-1100 is a small molecule inhibitor of aspartyl-(asparaginyl)-β-hydroxylase (ASPH), inhibits the β-hydroxylase activity of ASPH about 80%, inhibits Notch signaling in HCC cancer cells. |
| PC-49272 |
CRS0540
PolC inhibitor
|
CRS0540 is a potent, selective PolC DNA polymerase inhibitor that has demonstrated good in vitro and in vivo activity against Listeria monocytogenes. |
| PC-38598 |
Azo-resveratrol
Tyrosinase inhibitor
|
Azo-resveratrol is a potent mushroom tyrosinase inhibitor with IC50 of 36.28 uM. |
| PC-38531 |
ML266
GCase chaperone
|
ML266 (CID 46943215) is a non-inhibitory chaperone of glucocerebrosidase (GCase) enzyme, does not inhibit the enzyme’s action, but can facilitate its translocation to the lysosome. |
