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Chemical Structure : HTRA1 inhibitor 17
Catalog No.: PC-22463Not For Human Use, Lab Use Only.
HTRA1 inhibitor 17 is a highly potent and selective inhibitor of high temperature requirement A serine peptidase 1 (HTRA1) serine protease with IC50 of 13 nM.
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HTRA1 inhibitor 17 is a highly potent and selective inhibitor of high temperature requirement A serine peptidase 1 (HTRA1) serine protease with IC50 of 13 nM.
HTRA1 inhibitor 17 only weakly inhibits chymotrypsin, kallikrein 7, caspase 6 and caspase 9 in a panel of 35 proteases.
| M.Wt | 583.96 | |
| Formula | C31H43BClN3O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Dennis DG, et al. Bioorg Med Chem Lett. 2024 May 28:129814.
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