You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets-HTRA1 inhibitor 10
HTRA1 inhibitor 10

Chemical Structure : HTRA1 inhibitor 10

CAS No.:

HTRA1 inhibitor 10

Catalog No.: PC-22462Not For Human Use, Lab Use Only.

HTRA1 inhibitor 10 is a highly potent and selective inhibitor of high temperature requirement A serine peptidase 1 (HTRA1) serine protease with IC50 of 10 nM.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

HTRA1 inhibitor 10 is a highly potent and selective inhibitor of high temperature requirement A serine peptidase 1 (HTRA1) serine protease with IC50 of 10 nM.
HTRA1 inhibitor 10 only weakly inhibits chymotrypsin, kallikrein 7, caspase 6 and caspase 9 in a panel of 35 proteases.

Physicochemical Properties

M.Wt 545.87
Formula C27H37BClN3O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

((5S,8S,11R)-5-(3-chlorobenzyl)-8-isobutyl-12-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-11-yl)boronic acid

References

1. Dennis DG, et al. Bioorg Med Chem Lett. 2024 May 28:129814.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: