| Cat. No. |
Product Name |
Information |
| PC-49847 |
EP055
Sperm EPPIN inhibitor
|
EP055 (EP-055) is a small molecule that targets EPPIN on the surface of sperm and inhibits motility (IC50=199.5 uM, CASA assay using human sperm), binds to the C-terminal domain of EPPIN. |
| PC-49816 |
SS-1-148
hOAT inhibitor
|
SS-1-148 is a potent, selective inhibitor of human ornithine δ-aminotransferase (hOAT) with Ki of 60 uM, shows excellent selectivity over other related aminotransferases (e.g., GABA-AT). |
| PC-49815 |
OV329
GABA-AT inhibitor
|
OV329 (OV 329) is a highly potent inactivator of gamma-aminobutyric acid aminotransferase (GABA-AT) with Ki of 9.69 uM. |
| PC-49807 |
Muramyl Dipeptide
|
Muramyl Dipeptide is a naturally occurring component of bacterial cell walls that has the capacity to activate macrophages, is an immunological adjuvant. |
| PC-49803 |
ClpP agonist TR-65
|
ClpP agonist TR-65 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 23.3 nM. |
| PC-49802 |
ClpP agonist TR-57
|
ClpP agonist TR-57 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 15.5 nM. |
| PC-49801 |
ClpP agonist TR-27
|
ClpP agonist TR-27 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 23.7 nM. |
| PC-49766 |
CNS-11
Alpha-synuclein inhibitor
|
CNS-11 is a small molecules capable of disassembling preformed alpha-synuclein fibrils, may exert it's disaggregating effects on the N terminus of the fibril core. |
| PC-49756 |
NB-598 maleate
Squalene epoxidase inhibitor
|
NB-598 (NB598) is a potent competitive inhibitor of squalene epoxidase (SQLE, SE, squalene monooxygenase) with IC50 of 4.4 nM (rat SE), inhibits microsomal squalene epoxidase from dog liver and Hep G2 cells with IC50 of 2.0 and 0.75 nM, respectively. |
| PC-49755 |
MM0299 analog 13
Lanosterol synthase inhibitor
|
MM0299 analog 13 (MM 0299 derivative 13) is a potent, selective, orally bioavailable, brain-penetrant inhibitor of lanosterol synthase (LSS, competition EC50=28.7 nM) with anti-proliferative activity. |
| PC-49751 |
Cl-NIO
DDAH-1 inhibitor
|
Cl-NIO is a potent, selective inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with Ki of 1.3 uM, > 500-fold selectivity against arginase and endothelial nitric oxide synthase. |
| PC-49743 |
M50054
Apoptosis inhibitor
|
M50054 (M 50054) is a small molecule inhibitor of apoptosis (programmed cell death), inhibits soluble human Fas ligand-induced cell death of human Fasexpressing WC8 cells with IC50 of 67 ug/mL. |
