| Cat. No. |
Product Name |
Information |
| PC-61855 |
Elamipretide
|
Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell type. |
| PC-61825 |
NS-3-008
G0/G1 switch 2 inhibitor
|
NS-3-008 is a novel small-molecule transcriptional inhibitor of G0s2 (G0/G1 switch 2) with IC50 of 2.25 uM. |
| PC-61820 |
UK-396082
TAFIa inhibitor
|
UK-396082 is a potent and selective inhibitor of activated thrombin-activatable fibrinolysis inhibitor (activated TAFI, TAFIa) with Ki of 10 nM. |
| PC-61813 |
FEN1-IN-C20
FEN1 inhibitor
|
FEN1-IN-C20 is an N‐hydroxyl urea derivative that specifically inhibits flap endonuclease 1 (FEN1) activity with IC50 of 3 nM. |
| PC-61796 |
Trofinetide
|
Trofinetide (NNZ 2566) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration. |
| PC-61795 |
Cromoglicic acid
Mast cell stabilizer
|
Cromoglicic acid (Cromolyn, FPL-670) is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells. |
| PC-61794 |
Sodium cromoglicate
Mast cell stabilizer
|
Sodium cromoglicate is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells. |
| PC-61784 |
NSC 15765
DNA2 nuclease inhibitor
|
NSC 15765 (Compound C5, DNA2 inhibitor C5) is an effective, selective and competitive inhibitor of DNA2 nuclease with IC50 of 20 uM. |
| PC-61782 |
J147
Neuroprotective agent
|
J 147 is a potent, orally active, memory enhancing and neurotrophic agent that protects against neurotoxicity in cortical neurons in vitro with EC50 of 25-200 nM. |
| PC-61781 |
CAD-031
Neuroprotective agent
|
CAD-031 (CAD31) is a novel brain penetrant, J147-derivative that has enhanced neurogenic activity over J147 in human neural precursor cells (NPCs). |
| PC-61734 |
R-283
hTG2 inhibitor
|
R-283 is a potent and selective human tissue transglutaminase (hTG2) inhibitor with IC50 of 4 uM.. |
| PC-61730 |
FPPS inhibitor OX14
FPPS inhibitor
|
OX14 is a highly potent farnesyl pyrophosphate synthase (FPPS) inhibitor with IC50 of 2.46 nM, with significantly lower binding affinity to hydroxyapatite. |
