| Cat. No. |
Product Name |
Information |
| PC-38773 |
LSALT peptide
DPEP-1 inhibitor
|
Metablok (LSALT peptide) is a specific DPEP1-binding peptide and nonenzymatic dipeptidase-1 (DPEP-1) inhibitor. |
| PC-38767 |
S202
Ceramide galactosyltransferase inhibitor
|
S202 is a potent, selective and brain-penetrant small molecule inhibitor of ceramide galactosyltransferase (CGT) with IC50 of 15 nM in the cell-lysate assays and 3.6 nM in intact-cell assays. |
| PC-38737 |
CQ211
RIOK2 inhibitor
|
CQ211 is a potent, highly selective RIOK2 inhibitor with Kd of 6.1 nM, shows excellent selectivity to RIOK2 in both enzymatic and cellular assays. |
| PC-38722 |
GO-Y078
Angiogenesis inhibitor
|
GO‐Y078 is a curcumin analog that suppresses angiogenesis through the inhibition of actin stress fiber formation, inhibits human umbilical venous epithelial cells resistant to angiogenesis inhibitors (HUVEC‐R) at 0.75 uM. |
| PC-38711 |
TFF3 inhibitor AMPC
TFF3 inhibitor
|
AMPC is a first-in-class small-molecule inhibitor of the oncogenic functions of trefoil factor 3 (TFF3) that specifically monomerizes dimeric TFF3 to inhibit dimeric TFF3 function, specifically binds to Cys57 of TFF3. |
| PC-38705 |
AF615
CDT1/Geminin inhibitor
|
AF615 is a potent and selective small-molecule inhibitor targeting the CDT1/Geminin protein complex with Ki of 0.37 uM aginst Geminin-tCDT1 interaction, inhibits inhibit Geminin/CDT1 complex formation in vitro with IC50 of 0.313 uM. |
| PC-38700 |
ALKBH5 inhibitor 20m
ALKBH5 inhibitor
|
ALKBH5 inhibitor 20m is a potent, selective RNA m6A demethylase AlkB homolog 5 (ALKBH5) inhibitor with IC50 of 21 nM. |
| PC-38697 |
PAANIB-1
PAAN/MIF nuclease inhibitor
|
PAANIB-1 is a brain-penetrant PAAN/MIF nuclease inhibitor that prevents neurodegeneration that prevents neurodegeneration induced by α-syn PFF, AAV-α-syn overexpression, or MPTP intoxication in vivo. |
| PC-38675 |
Ninerafaxstat trihydrochloride
|
Ninerafaxstat (CV-8972) is a small molecule compound that promotes glucose oxidation, decreases fatty acid oxidation and improve overall mitochondrial respiration, inhibits the growth and proliferation of cancer cells. |
| PC-38674 |
Ninerafaxstat
|
Ninerafaxstat (CV-8972) is a small molecule compound that promotes glucose oxidation, decreases fatty acid oxidation and improve overall mitochondrial respiration, inhibits the growth and proliferation of cancer cells. |
| PC-38658 |
DS69910557
hPTHR1 antagonist
|
DS69910557 is a highly potent, selective orally available human parathyroid hormone receptor 1 (hPTHR1) antagonist. |
| PC-38655 |
ELOVL1-IN-27
ELOVL1 inhibitor
|
ELOVL1-IN-27 is a highly potent, selective, CNS-penetrant inhibitor of elongation of very long chain fatty acid 1 enzyme (ELOVL1) with IC50 of 13 nM (C26:0 VLCFA inhibition in HEK cell). |
