| Cat. No. |
Product Name |
Information |
| PC-73090 |
IPA
SNARE inhibitor
|
IPA (Inhibitor of Priming Activity) is a small-molecule compound that binds Sec18 (Kd=3.84 uM) and blocks SNARE activation, inhibits vacuole fusion at the SNARE priming stage with IC50 of 50 uM. |
| PC-73087 |
BRD4780
TMED9 inhibitor
|
BRD4780 is a small molecule that releases MUC1-fs from TMED9-enriched compartments and promotes its anterograde trafficking to the lysosome, directly binds to TMED9. |
| PC-73086 |
TMPRSS6 inhibitor Cpd-B
TMPRSS6 inhibitor
|
TMPRSS6 inhibitor Cpd-B (TMPRSS6-IN-Cpd-B) is a highly potent (IC50=7.6 nM), specific small molecule inhibitor of TMPRSS6 (matriptase-2). |
| PC-73085 |
TMPRSS6 inhibitor 8
TMPRSS6 inhibitor
|
TMPRSS6 inhibitor 8 (TMPRSS6-IN-8) is a highly potent (IC50=8.1 nM), peptidomimetic inhibitor of TMPRSS6 (matriptase-2). |
| PC-73083 |
SPI-21
Spt5-Pol II inhibitor
|
SPI-21 (Spt5-Pol II inhibitor 21) is a small-molecule inhibitor of Spt5-Pol II with IC50 of 25.2 uM. |
| PC-73082 |
Endosidin17
VPS35 inhibitor
|
Endosidin17 (ES17) is a small molecule targets retromer component VPS35, binds to VPS35 Impairs interaction with RABG3f, causes dose-dependent stabilization of VPS35 with EC50 of 0.9 uM. |
| PC-73077 |
PCC0208017
pan-MARK inhibitor
|
PCC0208017 is a potent, selective dual small-molecule inhibitor of MARK3 and MARK4 with IC50 of 1.8 and 2.01 nM, respectively. |
| PC-73073 |
Perforin inhibitor 16
Perforin inhibitor
|
Perforin inhibitor 16 (Perforin-IN-16) is a small molecule Perforin inhibitor with IC50 of 1.13 uM in KHYG1 assay. |
| PC-73066 |
SCO-792
Enteropeptidase inhibitor
|
SCO-792 (SCO792) is a potent, selective, reversible enteropeptidase inhibitor with IC50 of 4.6 and 5.4 nM for rat and human enteropeptidase, respectively. |
| PC-73065 |
ASB17061
Chymase inhibitor
|
ASB17061 (ASB-17061) is an orally active, selective chymase inhibitor with IC50 of 0.03 uM and 0.02 uM for mMCP-4 and human chymase, respecitvely. |
| PC-73058 |
SWE101
sEH-P inhibitor
|
SWE101 (SWE-101, SWE 101) is a potent, selective, in vivo active inhibitor of soluble epoxide hydrolase (sEH) phosphatase domain (sEH-P) with IC50 of 58 nM. |
| PC-73057 |
AZ67
PFKFB3 inhibitor
|
AZ67 is a selective small molecule PFKFB3 inhibitor with IC50 of 18 nM, reduces cellular levels of F2,6BP with IC50 of 0.51 uM. |
