| Cat. No. |
Product Name |
Information |
| PC-73139 |
ASN90
O-GlcNAcase inhibitor
|
ASN90 is a potent, selective, substrate-competitive O-GlcNAcase (OGA) inhibitor with IC50 of 10.2 nM. |
| PC-73138 |
KVD900
Plasma kallikrein inhibitor
|
Sebetralstat (KVD900) is a potent, selective, competitive and reversible inhibitor of human plasma kallikrein (PKa) enzyme with Ki of 3.02 nM. |
| PC-73136 |
Naphthyridine-azaquinolone
Slipped-CAG DNA binder
|
Naphthyridine-azaquinolone (NA) is a specific small molecule that specifically binds slipped-CAG DNA intermediates of expansion mutations. |
| PC-73135 |
PGAM1 inhibitor KH3
PGAM1 inhibitor
|
PGAM1 inhibitor KH3 is a potent, allosteric small molecule inhibitor of phosphoglycerate mutase 1 (PGAM1) with IC50 of 105 nM. |
| PC-73129 |
HG106
SLC7A11 inhibitor
|
HG106 (HG 106) is a potent, selective SLC7A11 inhibitor, selectively kills KRAS-mutant lung adenocarcinoma (LUAD) cells. |
| PC-73123 |
CU-76
cGAS inhibitor
|
CU-76 (cGAS inhibitor CU-76) is a small-molecule human cGAS (hcGAS) inhibitor with IC50 of 0.24 uM. |
| PC-73115 |
AZD9898
LTC4S inhibitor
|
AZD9898 (AZD-9898) is a highly potent, selective and oral inhibitor of leukotriene C4 synthase (LTC4S) with IC50 of 0.28 nM. |
| PC-73111 |
S-181
GCase activator
|
S-181 (S 181) is a specific small-molecule activator (modulator) of β-glucocerebrosidase (GCase) with AC50 of 1.49 uM and a maximum activation of 780%. |
| PC-73103 |
GNF362
ITPKB inhibitor
|
GNF362 (GNF-362) is a highly potent, selective inhibitor of inositol 1,4,5-trisphosphate 3-kinase B (ITPKB) with IC50 of 9 nM. |
| PC-73101 |
VIT-2763
Ferroportin inhibitor
|
VIT-2763 (Vamifeport, VIT2763) is an oral small molecule inhibitor of ferroportin, inhibits hepcidin binding to ferroportin with IC50 of 9 nM, blocks iron efflux. |
| PC-73090 |
IPA
SNARE inhibitor
|
IPA (Inhibitor of Priming Activity) is a small-molecule compound that binds Sec18 (Kd=3.84 uM) and blocks SNARE activation, inhibits vacuole fusion at the SNARE priming stage with IC50 of 50 uM. |
| PC-73087 |
BRD4780
TMED9 inhibitor
|
BRD4780 is a small molecule that releases MUC1-fs from TMED9-enriched compartments and promotes its anterograde trafficking to the lysosome, directly binds to TMED9. |
