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Chemical Structure : ALKBH5 inhibitor 20m
CAS No.: 126067-60-5
Catalog No.: PC-38700Not For Human Use, Lab Use Only.
ALKBH5 inhibitor 20m is a potent, selective RNA m6A demethylase AlkB homolog 5 (ALKBH5) inhibitor with IC50 of 21 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $298 | In stock | |
| 10 mg | $458 | In stock | |
| 25 mg | $758 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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ALKBH5 inhibitor 20m is a potent, selective RNA m6A demethylase AlkB homolog 5 (ALKBH5) inhibitor with IC50 of 21 nM.
ALKBH5 inhibitor 20m exhibits high selectivity towards ALKBH5 versus FTO as well as other AlkB subfamily members (IC50>25 uM).
ALKBH5 inhibitor 20m could efficiently stabilize ALKBH5 and increase m6A level in intact cells.
| M.Wt | 270.211 | |
| Formula | C12H9F3N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
5-methyl-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylic acid |
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1. ZhenFang, et al. European Journal of Medicinal Chemistry, 11 May 2022, 114446.
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