| Cat. No. |
Product Name |
Information |
| PC-62032 |
LCS-1.28
SOD1 inhibitor
|
LCS-1.28 is a small molecule that inhibits growth of human lung adenocarcinoma cells harboring mutations in EGFR or KRAS with IC50 of 0.05-1.6 uM. |
| PC-62031 |
LCS-1
SOD1 inhibitor
|
LCS-1 is a small molecule that inhibits growth of human lung adenocarcinoma cells harboring mutations in EGFR or KRAS with IC50 of 0.1-1.5 uM. |
| PC-62028 |
BRD8899
STK33 inhibitor
|
BRD 8899 is a potent and selective inhibitor of the serine/threonine kinase STK33 with IC50 of 0.11 nM (25 uM ATP). |
| PC-62025 |
FQI2
LSF inhibitor
|
FQI2 is a small-molecule inhibitor of transcription factor LSF with IC50 of 0.71 uM. |
| PC-62024 |
(S)-FQI1
LSF inhibitor
|
(S)-FQI1 is a small-molecule inhibitor of transcription factor LSF with IC50 of 0.93 uM, approximately 2-fold more active than the racemate FQI-1. |
| PC-61994 |
TK216
EWS-FLI1 inhibitor
|
TK216 is a first in class, small molecule that directly binds EWS-FLI1 inhibiting the biological activity of ETS-family transcription factor oncoproteins and is currently under clinical investigation against Ewing sarcoma.. |
| PC-61918 |
Cyclocreatine Phosphate
Creatine kinase inhibitor
|
Cyclocreatine Phosphate (AM 285) is an analog of the creatine kinase CKMT1 substrate creatine and inhibitor of the creatine biosynthesis pathway. |
| PC-61855 |
Elamipretide
|
Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell type. |
| PC-61825 |
NS-3-008
G0/G1 switch 2 inhibitor
|
NS-3-008 is a novel small-molecule transcriptional inhibitor of G0s2 (G0/G1 switch 2) with IC50 of 2.25 uM. |
| PC-61820 |
UK-396082
TAFIa inhibitor
|
UK-396082 is a potent and selective inhibitor of activated thrombin-activatable fibrinolysis inhibitor (activated TAFI, TAFIa) with Ki of 10 nM. |
| PC-61813 |
FEN1-IN-C20
FEN1 inhibitor
|
FEN1-IN-C20 is an N‐hydroxyl urea derivative that specifically inhibits flap endonuclease 1 (FEN1) activity with IC50 of 3 nM. |
| PC-61796 |
Trofinetide
|
Trofinetide (NNZ 2566) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration. |
