| Cat. No. |
Product Name |
Information |
| PC-62311 |
PF-9366
MAT2A inhibitor
|
PF-9366 is a novel selective, allosteric methionine adenosyltransferase 2A (Mat2A) inhibitor with IC50 of 420 nM, Kd of 170 nM. |
| PC-62300 |
FEN1-IN-1
FEN1/EXO1 inhibitor
|
FEN1-IN-1 (FEN1i-1, LNT1) is a potent, selective Flap Endonuclease-1 (FEN1) inhibitor with IC50 of 11 nM, inhibits FEN1 and EXO1 with equal potency and specificity. |
| PC-62296 |
Miquelianin
|
Miquelianin (Quercetin-3-O-glucuronide) is a flavonol glucuronide that shows an antioxidant effect in human plasma, also is a CBR1 inhibitor. |
| PC-62259 |
Inflachromene
HMGB1 inhibitor
|
Inflachromene (ICM) is a microglial inhibitor with anti-inflammatory effects, directly binds high mobility group protein 1 (HMGB1) and HMGB2 and reduces their cytoplasmic accumulation in microglial cells. |
| PC-62257 |
Jarin-1
JAR1 inhibitor
|
Jarin-1 is the first small-molecule inhibitor of JAR1 (IC50=3.8 uM) that inhibits jasmonate responses in Arabidopsis thaliana. |
| PC-62253 |
WWL113
Ces3 inhibitor
|
WWL113 is a potent inhibitor of Carboxylesterase Ces3 and Ces1f by competitive ABPP of enzymes recombinantly expressed in HEK293T cells (IC50 value of 0.1 uM for each enzyme). |
| PC-62252 |
WWL229
Ces3 inhibitor
|
WWL229 is a selective, distinct Carboxylesterase Ces3 inhibitor with IC50 of 1.94 uM, but not Ces1f, ABHD6, other serine hydrolases. |
| PC-62245 |
Triphenyl compound A
Pirin inhibitor
|
Triphenyl compound A (TPh A) is a small-molecule inhibitor of nuclear protein Pirin with Kd of 0.6 uM, inhibits the interaction between pirin and Bcl3 in vitro and in cells. |
| PC-62237 |
Isomigrastatin
Cancer migration inhibitor
|
Isomigrastatin (iso-Migrastatin) is an analogue of migrastatin that shows potent antiproliferative effect on tumor cell lines and selectively inhibits translation. |
| PC-62235 |
Dorrigocin A
|
Dorrigocin A is a natural compound that shows potent antiproliferative effect on tumor cell line.. |
| PC-62234 |
Golgicide A
ArfGEF GBF1 inhibitor
|
Golgicide A is a potent, highly specific, reversible inhibitor of the cis-Golgi ArfGEF GBF1, inhibits the effect of shiga toxin on protein synthesis with IC50 of 3.3 uM. |
| PC-62222 |
BF844
CLRN1(N48K) stabilizer
|
BF844 (BioFocus 844) is a small molecules capable of stabilizing mutant USH3 mutation CLRN1(N48K). |
