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Adhesamine

Chemical Structure : Adhesamine

CAS No.: 462605-73-8

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Adhesamine

Catalog No.: PC-62425Not For Human Use, Lab Use Only.

Adhesamine is a diaryldispirotripiperazine derivative that selectively targets cell-surface glycosaminoglycans, especially heparan sulfate, for increasing cell adhesion and growth.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Adhesamine is a diaryldispirotripiperazine derivative that selectively targets cell-surface glycosaminoglycans, especially heparan sulfate, for increasing cell adhesion and growth.
    Adhesamine induces apparently normal cell adhesion accompanied by organized actin structures and activation of focal adhesion kinase and ERK1/2 mitogen-activated protein kinases.
    Adhesamine is a cell-attaching reagent for cell engineering and basic cell biology.

    Physicochemical Properties

    M.Wt 670.494
    Formula C24H32Cl4N8O2S2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    3,12-bis(6-chloro-5-formyl-2-(methylthio)pyrimidin-4-yl)-3,6,9,12-tetraazadispiro[5.2.59.26]hexadecane-6,9-diium chloride

    References

    1. Yamazoe S, et al. Chem Biol. 2009 Jul 31;16(7):773-82.

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