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Antimycin A

Chemical Structure : Antimycin A

CAS No.: 1397-94-0

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Antimycin A

Catalog No.: PC-62434Not For Human Use, Lab Use Only.

Antimycin A is an inhibitor of cellular respiration, specifically oxidative phosphorylation, binds to the Qi site of cytochrome c reductase, disrupts the Q-cycle of enzyme turn over.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Antimycin A is an inhibitor of cellular respiration, specifically oxidative phosphorylation, binds to the Qi site of cytochrome c reductase, disrupts the Q-cycle of enzyme turn over.
    Antimycin A also inhibits the cyclic electron flow within photosynthetic systems

    Physicochemical Properties

    M.Wt 548.63
    Formula C28H40N2O9
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    [(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate

    References

    1. Kim, H, et al. J. Am. Chem. Soc.1999 (4902): 121.

    2. Dairaku N, et al. J Lab Clin Med. 2004 Mar;143(3):143-51.

    3. Taira Y, et al. FEBS Open Bio. 2013 Sep 30;3:406-10.

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