| Cat. No. |
Product Name |
Information |
| PC-62259 |
Inflachromene
HMGB1 inhibitor
|
Inflachromene (ICM) is a microglial inhibitor with anti-inflammatory effects, directly binds high mobility group protein 1 (HMGB1) and HMGB2 and reduces their cytoplasmic accumulation in microglial cells. |
| PC-62257 |
Jarin-1
JAR1 inhibitor
|
Jarin-1 is the first small-molecule inhibitor of JAR1 (IC50=3.8 uM) that inhibits jasmonate responses in Arabidopsis thaliana. |
| PC-62253 |
WWL113
Ces3 inhibitor
|
WWL113 is a potent inhibitor of Carboxylesterase Ces3 and Ces1f by competitive ABPP of enzymes recombinantly expressed in HEK293T cells (IC50 value of 0.1 uM for each enzyme). |
| PC-62252 |
WWL229
Ces3 inhibitor
|
WWL229 is a selective, distinct Carboxylesterase Ces3 inhibitor with IC50 of 1.94 uM, but not Ces1f, ABHD6, other serine hydrolases. |
| PC-62245 |
Triphenyl compound A
Pirin inhibitor
|
Triphenyl compound A (TPh A) is a small-molecule inhibitor of nuclear protein Pirin with Kd of 0.6 uM, inhibits the interaction between pirin and Bcl3 in vitro and in cells. |
| PC-62237 |
Isomigrastatin
Cancer migration inhibitor
|
Isomigrastatin (iso-Migrastatin) is an analogue of migrastatin that shows potent antiproliferative effect on tumor cell lines and selectively inhibits translation. |
| PC-62235 |
Dorrigocin A
|
Dorrigocin A is a natural compound that shows potent antiproliferative effect on tumor cell line.. |
| PC-62234 |
Golgicide A
ArfGEF GBF1 inhibitor
|
Golgicide A is a potent, highly specific, reversible inhibitor of the cis-Golgi ArfGEF GBF1, inhibits the effect of shiga toxin on protein synthesis with IC50 of 3.3 uM. |
| PC-62222 |
BF844
CLRN1(N48K) stabilizer
|
BF844 (BioFocus 844) is a small molecules capable of stabilizing mutant USH3 mutation CLRN1(N48K). |
| PC-62221 |
ML239
FADS2 inhibitor
|
ML239 is a selective small molecule inhibitor of breast cancer stem cells with IC50 of 1.18 uM, displays >23-fold selective inhibition of the breast CSC-like cell line over the isogenic control cell line. |
| PC-62204 |
AA41612
OPN4 antagonist
|
AA 41612 is a potent, synthetic melanopsin antagonist with IC50 of 15.8 nM, attenuates melanopsin photocurrent in a dose-dependent manner. |
| PC-62200 |
7DG
PKR inhibitor
|
7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR) that directly interact with the C-terminal of PKR. |
