| Cat. No. |
Product Name |
Information |
| PC-62367 |
BRD5459
ROS inducer
|
BRD5459 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer.. |
| PC-62363 |
MN30
APOBEC3G inhibitor
|
MN30 (Methyl-3,4-dephostatin, APOBEC3G inhibitor MN30) is a first-in-class, selectve small molecule inhibitor of the single-strand DNA cytosine deaminase APOBEC3G with IC50 of 9.1 uM. |
| PC-62361 |
Aurintricarboxylic acid
|
NSC4056 (Aurintricarboxylic acid) is a potent, bioactive inhibitor of cystathionine γ-lyase (CSE) with IC5 of 0.6 uM, also is a selective inhibitor of the TWEAK-Fn14 signaling pathway. |
| PC-62356 |
BIO 8898
CD40L inhibitor
|
BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM. |
| PC-62343 |
Deoxynyboquinone
NQO1 substrate
|
Deoxynyboquinone (NSC 165572, DNQ) is a potent inducer of cancer cell death that induces death of cancer cells in culture with IC50 of 16-210 nM, a substrate for NAD(P)H:quinone oxidoreductase (NQO1). |
| PC-62342 |
Isobutyl-deoxynyboquinone
NQO1 substrate
|
Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1), produces ROS, and induces cytotoxicity in cancer cells in an NQO1-dependent manner. |
| PC-62316 |
UM171
HSC self-renewal agonist
|
UM171 (UM-171) is a potent agonist of human hematopoietic stem cell (HSC) self-renewal, shows 10 to 20 times more potent than UM729 with effective concentrations of 17 to 19 nM. |
| PC-62311 |
PF-9366
MAT2A inhibitor
|
PF-9366 is a novel selective, allosteric methionine adenosyltransferase 2A (Mat2A) inhibitor with IC50 of 420 nM, Kd of 170 nM. |
| PC-62300 |
FEN1-IN-1
FEN1 inhibitor
|
FEN1-IN-1 is a potent, selective Flap Endonuclease-1 (FEN1) inhibitor with IC50 of 11 nM. |
| PC-62296 |
Miquelianin
|
Miquelianin (Quercetin-3-O-glucuronide) is a flavonol glucuronide that shows an antioxidant effect in human plasma, also is a CBR1 inhibitor. |
| PC-62259 |
Inflachromene
HMGB1 inhibitor
|
Inflachromene (ICM) is a microglial inhibitor with anti-inflammatory effects, directly binds high mobility group protein 1 (HMGB1) and HMGB2 and reduces their cytoplasmic accumulation in microglial cells. |
| PC-62257 |
Jarin-1
JAR1 inhibitor
|
Jarin-1 is the first small-molecule inhibitor of JAR1 (IC50=3.8 uM) that inhibits jasmonate responses in Arabidopsis thaliana. |
