| Cat. No. |
Product Name |
Information |
| PC-62411 |
GPI 16552
PARG inhibitor
|
GPI 16552 is a potent, specific poly(ADP-ribose) glycohydrolase (PARG) inhibitor with IC50 of 1.7 uM. |
| PC-62403 |
CI-976
ACAT-1 inhibitor
|
CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM, also inhibits sterol O-acyltransferase 1 (SOAT1) with IC50 of 6.95 uM (hSOAT1). |
| PC-62394 |
AGPS inhibitor 1a
AGPS inhibitor
|
AGPS inhibitor 1a (AGPS-IN-1a) is a potent inhibitor of the ether lipid-generating enzyme alkyl-glycerone phosphate synthase (AGPS), selectively lowers ether lipid levels in several types of human cancer cells and impairs their cellular survival and migration. |
| PC-62388 |
ML358
SKN-1 inhibitor
|
ML358 is a first in class, selective small molecule inhibitor of the SKN-1 pathway with IC50 of 0.24 uM. |
| PC-62387 |
OSMI-1
O-GlcNAc transferase inhibitor
|
OSMI-1 is a cell-permeable, small molecule O-GlcNAc transferase (OGT) inhibitor with IC50 of 2.7 uM. |
| PC-62386 |
P11
PAFAH inhibitor
|
PAFAH inhibitor P11 (P11) is a potent, selective platelet-activating factor acetylhydrolases PAFAH1b2 and PAFAH1b3 inhibitor with IC50 of 40 nM and 900 nM respectively. |
| PC-62382 |
RH01687
|
RH01687 is a small molecule that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death. |
| PC-62380 |
TD-1
Hemoglobin modulator
|
Hemoglobin modulator TD-1 (TD-1) is a novel allosteric effector of hemoglobin that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling. |
| PC-62379 |
BCI-137
|
BCI-137 is a chemical compound able to compete with Argonaute 2 miRNAs binding, binds to Ago2 with Kd of 126 uM. |
| PC-62369 |
BRD56491
ROS inducer
|
BRD56491 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer.. |
| PC-62368 |
BRD9092
ROS inducer
|
BRD9092 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer.. |
| PC-62367 |
BRD5459
ROS inducer
|
BRD5459 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer.. |
