You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets

Request The Product List ofOther Targets Other Targets

Cat. No. Product Name Information
PC-49726

Seletracetam

SV2A ligand

Seletracetam (ucb 44212) is a high affinity for the synaptic vesicle protein 2A (SV2A) than levetiracetam with 10-fold, exhibits anticonvulsant properties in animal models of epilepsy.
PC-49704

NUP-17d-52A

Plek2 inhibitor

NUP-17d-52A (Plek2 inhibitor) is a specific small molecule inhibitor of Pleckstrin-2 (Plek2), binds to Plek2-DEP domain with high affinity (Kd=160 nM).
PC-49703

Plek2 inhibitor NUP-17d

Plek2 inhibitor

Plek2 inhibitor NUP-17d is a specific small molecule inhibitor of Pleckstrin-2 (Plek2), binds to Plek2 and Plek2-DEP with high affinity (ITC KD=109 and 350 nM, respectively).
PC-49693

Xist inhibitor X1

Xist inhibitor

Xist inhibitor X1 is a selective small molecule inhibitor of the non-coding RNA prototype Xist function, binds specifically to the RepA motif of Xist (Kd=0.4 uM) in vitro and in vivo.
PC-49690

Novobiocin

POLθ inhibitor

Novobiocin (NVB) is a potent, specific DNA polymerase theta (POLθ, POLQ) inhibitor with IC50 of 24 uM, selectively kills HR-deficient tumor cells in vitro and in vivo.
PC-49685

MPO inhibitor IN-4

MPO inhibitor

MPO inhibitor IN-4 is a highly potent, selective, irreversible and orally bioavailable myeloperoxidase (MPO) inhibitor.
PC-49680

ART899

DNA Polθ inhibitor

ART899 (ART-899) is a potent, specific allosteric inhibitor of DNA polymerase theta (Polθ), specifically inhibits Polθ MMEJ activity with IC50 of 180 nM, shows with improved in vivo stability compared to ART558.
PC-49648

FK3453

TSLP inhibitor

FK3453 (FK 3453) is a novel inhibitor of thymic stromal lymphopoietin (TSLP) production, reduces both TSLP protein levels and mRNA levels both in vitro and in vivo.
PC-49645

TH8535

OGG1 inhibitor

TH8535 (TH-8535) is a potent, selective inhibitor of 8-oxo Guanine DNA Glycosylase 1 (OGG1) with IC50 of 0.2 uM.
PC-49631

Brivaracetam

SV2A ligand

Brivaracetam (UCB 34714) is a potent, selective synaptic vesicle protein 2A (SV2A) ligand with pKi of 6.5, 20-fold more potent than Levetiracetam (Cat# PC49630), shows anticonvulsant activities in audiogenic mice.
PC-49630

Levetiracetam

SV2A ligand

Levetiracetam (UCB L059) an antiepileptic drug with a unique activity profile in animal models of seizure and epilepsy, binds to (pKi=5.2) and modulates synaptic vesicle protein SV2A.
PC-49607

NCP26

ProRS inhibitor

NCP26 is a potent, ATP-competitive prolyl-tRNA synthetase (ProRS, PRS) inhibitor, inhibits recombinant human ProRS in the presence of 100 μM proline with KD of 0.35 nM in TR-FRET assays.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com