PTGR2-IN-22 (PTGR2 inhibitor 22) |CAS 349093-44-3 Probechem Biochemicals

Chemical Structure : PTGR2 inhibitor 22

CAS No.: 349093-44-3

PTGR2 inhibitor 22 (PTGR2-IN-22)

Catalog No.: PC-62692Not For Human Use, Lab Use Only.

PTGR2-IN-22 (PTGR2 inhibitor 22) is a potent PTGR2 (prostaglandin reductase 2) ligand that inhibits 15-keto-PGE2 reductase activity with IC50 of 0.55 uM in HEK293T cells.

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$198	In stock
25 mg	$328	In stock
50 mg	$528	In stock
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Biological Activity

PTGR2-IN-22 (PTGR2 inhibitor 22) is a potent PTGR2 (prostaglandin reductase 2) ligand that inhibits 15-keto-PGE2 reductase activity with IC50 of 0.55 uM in HEK293T cells.
PTGR2-IN-22 also produces a concentration-dependent rescue of 15-keto-PGE2-dependent PPARγ transcriptional activity in cells recombinantly expressing PTGR2.

Physicochemical Properties

M.Wt	310.397
Formula	C19H22N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-(2-Methoxyphenyl)piperazin-1-yl)-2-phenylethan-1-one

References

1. Parker CG, et al. Cell. 2017 Jan 26;168(3):527-541.e29.

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PTGR2 inhibitor 22 (PTGR2-IN-22)

Biological Activity

Physicochemical Properties

References

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