Chemical Structure : PTGR2 inhibitor 22
CAS No.: 349093-44-3
Catalog No.: PC-62692Not For Human Use, Lab Use Only.
PTGR2-IN-22 (PTGR2 inhibitor 22) is a potent PTGR2 (prostaglandin reductase 2) ligand that inhibits 15-keto-PGE2 reductase activity with IC50 of 0.55 uM in HEK293T cells.
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PTGR2-IN-22 (PTGR2 inhibitor 22) is a potent PTGR2 (prostaglandin reductase 2) ligand that inhibits 15-keto-PGE2 reductase activity with IC50 of 0.55 uM in HEK293T cells.
PTGR2-IN-22 also produces a concentration-dependent rescue of 15-keto-PGE2-dependent PPARγ transcriptional activity in cells recombinantly expressing PTGR2.
M.Wt | 310.397 | |
Formula | C19H22N2O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-(4-(2-Methoxyphenyl)piperazin-1-yl)-2-phenylethan-1-one |
1. Parker CG, et al. Cell. 2017 Jan 26;168(3):527-541.e29.
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