VU6001221 | Choline transporter inhibitor

You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets-VU6001221

Chemical Structure : VU6001221

VU6001221 (VU 6001221)

Catalog No.: PC-62786Not For Human Use, Lab Use Only.

VU6001221 is a potent choline transporter (CHT) inhibitor with IC50 of 270 nM.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

VU6001221 is a potent choline transporter (CHT) inhibitor with IC50 of 270 nM.
VU6001221 shows comparable potency for choline uptake inhibition as ML352, yet improved PK and CNS penetration.
VU6001221 elicits a dose-responsive increase in NOR, raises the possibility of agonism of synaptic α7 nicotinic ACh receptors by elevated extracellular choline.

Physicochemical Properties

M.Wt	391.89
Formula	C20H26ClN3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzamide, 4-chloro-N-[[3-(1-methylethyl)-5-isoxazolyl]methyl]-3 -[(1-methyl-4-piperidinyl)oxy]-

References

1. Bertron JL, et al. Bioorg Med Chem Lett. 2016 Oct 1;26(19):4637-40.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

VU6001221 (VU 6001221)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.