Chemical Structure : SB1301
CAS No.: 2024548-03-4
Catalog No.: PC-62859Not For Human Use, Lab Use Only.
SB1301 (LIN28-Let-7 inhibitor) is a small-molecule inhibitor disrupting the protein-RNA interaction of LIN28 and Let-7 with FRET IC50 of 4 uM.
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5 mg | $228 | In stock | |
10 mg | $358 | In stock | |
25 mg | $558 | In stock | |
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SB1301 (LIN28-Let-7 inhibitor) is a small-molecule inhibitor disrupting the protein-RNA interaction of LIN28 and Let-7 with FRET IC50 of 4 uM.
SB1301 (LIN28-Let-7 inhibitor) enhances the production of let-7 miRNAs in Lin28-expressing cancer cells and reduces the level of let-7 target oncogene products.
M.Wt | 583.601 | |
Formula | C31H29N5O7 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-(7-(4-((benzyloxy)carbonyl)piperazin-1-yl)-4,4-dimethyl-8-nitrochromeno[4,3-c]pyrazol-1(4H)-yl)benzoic acid |
1. Lim D, et al. J. Am. Chem. Soc., 2016, 138 (41), pp 13630–13638
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