| Cat. No. |
Product Name |
Information |
| PC-38211 |
KLK6 inhibitor 42
KLK6 inhibitor
|
KLK6 inhibitor 42 is a first-in-class inhibitor of kallikrein‐related peptidase 6 (KLK6, IC50=1.57 uM) that promote the differentiation of OPCs into mature oligodendrocytes in vitro.. |
| PC-38207 |
COUP-TFII inhibitor CIA1
COUP-TFII inhibitor
|
CIA1 (COUP-TFII inhibitor A1) is a potent and specific inhibitor of COUP-TFII activity, inhibits COUP-TFII–driven NGFIA reporter expression with IC50 of 3.2 uM, disturbs COUP-TFII binding to FOXA1 to regulate target gene expression. |
| PC-38205 |
CYD19
Snail inhibitor
|
Snail inhibitor CYD19 (CYD19) is a small-molecule compound that binds to the zinc finger transcription factor Snail (Kd=0.18 uM), and disrupts Snail interaction with CBP/p300. |
| PC-38202 |
AE 51310
OPN4 antagonist
|
AE 51310 is a small-molecule inhibitor of Opsin 4/melanopsin (OPN4), has antitumor potential in patient-derived xenograft (PDX) tumors in mice.. |
| PC-38201 |
AA92593
OPN4 antagonist
|
AA92593 is a selective and competitive OPN4 (melanopsin) antagonist with IC50 of 665 nM. |
| PC-38194 |
AG-636
DHODH inhibitor
|
AG-636 (AG636) is a novel potent, selective, reversible and oral dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 17 nM. |
| PC-38179 |
VY-3-135
ACSS2 inhibitor
|
VY-3-135 is a potent, specific acetyl-CoA synthetase 2 (ACSS2) inhibitor with IC50 of 44 nM, does not inhibits AcCoA synthetase family member ACSS1 and ACSS3. |
| PC-38168 |
BO-264
TACC3 inhibitor
|
BO-264 (BO264) is a highly potent inhibitor of transforming acidic coiled-coil (TACC) family member TACC3 (IC50=188 nM). |
| PC-38167 |
CHD1L inhibitor 6
CHD1L inhibitor
|
CHD1L inhibitor 6 is the first-in-class small molecule inhibitor of oncogenic CHD1L with IC50 of 5.5 uM in cat-CHD1L ATPase assay. |
| PC-38165 |
SBI-183
QSOX1 inhibitor
|
SBI-183 is a small molecule that binds to and inhibits the enzymatic activity of Quiescin sulfhydryl oxidase 1 (QSOX1, Kd=20 uM). |
| PC-38164 |
DSRM-3716
SARM1 inhibitor
|
DSRM-3716 (DSRM3716, 5-iodoisoquinoline) is a potent and selective inhibitor of NADase SARM1 with IC50 of 75 nM, displays selectivity against various NAD metabolizing and pathway enzymes (e.g., NAMPT and NMNAT). |
| PC-38163 |
ITYR-DBRMD
DIO3 inhibitor
|
ITYR-DBRMD is a first-in-class inhibitor of enzyme iodothyronine deiodinase type 3 (DIO3) with antitumor effects both in vitro and in vivo. |
