| Cat. No. |
Product Name |
Information |
| PC-38272 |
NCT-504
PI5P4Kγ inhibitor
|
NCT-504 (NCT504) is a selective inhibitor of PI5P4Kγ with IC50 of 16 uM in 32P-ATP/PI5P incorporation assay, high selectivity against a panel of 442 kinases. |
| PC-38271 |
PI5P4K inhibitor 13
PI5P4K inhibitor
|
PI5P4K inhibitor 13 is a selective pan-PI5P4K covalent inhibitor with IC50 of 2.0/13 uM against PI5P4Kα/β, 100% inhibition of PI5P4Kγ at 1 uM (Kd=3.4 nM). |
| PC-38270 |
PI5P4Kγ inhibitor 40
PI5P4Kγ inhibitor
|
PI5P4Kγ inhibitor 40 is a selective, non-ATP-competitive, allosteric inhibitor of PI5P4Kγ with pIC50 of 6.2, does not inhibit PI5P4Kα/β with pIC50<4.6. |
| PC-38261 |
UNC4976
CBX7 modulator
|
UNC4976 (UNC-4976) is a potent cellular active positive allosteric modulator of CBX7, binds to CBX7 competitively with H3K27me3 peptides (IC50=20 nM), while increasing affinity for oligonucleotides. |
| PC-38260 |
UNC7040
CBX8 modulator
|
UNC7040 (UNC-7040) is a potent, specific positive allosteric modulator of CBX8 with EC50 of 0.84 uM in CBX8 reporter assays. |
| PC-38253 |
Aprotinin
Trypsin/Chymotrypsin inhibitor
|
Aprotinin is a single chain polypeptide isolated from bovine lung with antifibrinolytic and anti-inflammatory activities, inhibits trypsin and chymotrypsin with Ki of 0.06 pM and 9 nM respectively. |
| PC-38249 |
NR2F1 agonist C26
NR2F1 agonist
|
NR2F1 agonist C26 is a specific agonist of nuclear receptor NR2F1, significantly induces luciferase expression by 1.7- and 1.9-fold at 0.5 and 1 uM in RARE-luciferase bioassays. |
| PC-38248 |
PF-06835919
Ketohexokinase inhibitor
|
PF-06835919 (PF 06835919) is a first-in-class, potent, selective Ketohexokinase (KHK) inhibitor with IC50 of 10 nM (hKHK). |
| PC-38247 |
GSK716
Zα1-antitrypsin inhibitor
|
GSK716 (GSK-716) is a potent inhibitor of Z α1-antitrypsin polymerisation, binds to Zα1-antitrypsin with a high-affinity (pKD=8.5). |
| PC-38246 |
BAM15
Mitochondrial uncoupler
|
BAM15 (Mitochondrial uncoupler BAM15) is a potent protonophore that uncouples the mitochondria without depolarizing the plasma membrane, oxidative phosphorylation (OXPHOS) uncoupler. |
| PC-38243 |
mitoNEET Ligand-1
mitoNEET ligand
|
mitoNEET Ligand-1 (NL-1) is a small molecule ligand of mitoNEET, a protein that regulate the oxidative capacity of the mitochondria. |
| PC-38227 |
DCLK1-IN-1
DCLK1 inhibitor
|
DCLK1-IN-1 is the first potent, selective inhibitor of the DCLK1 and DCLK2 kinases with IC50 of 9.5 nM and 31 nM in binding assays, respectively. |
