| Cat. No. |
Product Name |
Information |
| PC-62048 |
MitoBloCK 6
Erv1 oxidase inhibitor
|
MitoBloCK 6 is a small molecule mitochondrial protein import blocker that inhibits Erv1 oxidase activity. |
| PC-62047 |
MitoBloCK 1
TIM22 inhibitor
|
MitoBloCK 1 is a small molecule inhibitor that blocks the import of substrates that use the TIM22 import pathway, but not TIM23 or the Mia40/Erv1 translocation pathways. |
| PC-62043 |
DM-PIT-1
PIP3 antagonist
|
DM-PIT-1 is a specific PIP3 antagonist that disrupts PIP3/Akt PH domain, PIP3/PDK1 PH domain, and PIP3/GRP1 PH domain with IC50 of 27.1 uM, 80.5 uM, and 35.5 uM, respectively. |
| PC-62042 |
PIT-1
PIP3 antagonist
|
PIT-1 is a specific PIP3 antagonist that disrupts PIP3/Akt PH domain binding with IC50 of 30 uM, Kd of 43.2 uM. |
| PC-62033 |
LCS-1.34
SOD1 inhibitor
|
LCS-1.34 is a small molecule that inhibits growth of human lung adenocarcinoma cells harboring mutations in EGFR or KRAS with IC50 of 0.1-1.1 uM. |
| PC-62032 |
LCS-1.28
SOD1 inhibitor
|
LCS-1.28 is a small molecule that inhibits growth of human lung adenocarcinoma cells harboring mutations in EGFR or KRAS with IC50 of 0.05-1.6 uM. |
| PC-62031 |
LCS-1
SOD1 inhibitor
|
LCS-1 is a small molecule that inhibits growth of human lung adenocarcinoma cells harboring mutations in EGFR or KRAS with IC50 of 0.1-1.5 uM. |
| PC-62028 |
BRD8899
STK33 inhibitor
|
BRD 8899 is a potent and selective inhibitor of the serine/threonine kinase STK33 with IC50 of 0.11 nM (25 uM ATP). |
| PC-62025 |
FQI2
LSF inhibitor
|
FQI2 is a small-molecule inhibitor of transcription factor LSF with IC50 of 0.71 uM. |
| PC-62024 |
(S)-FQI1
LSF inhibitor
|
(S)-FQI1 is a small-molecule inhibitor of transcription factor LSF with IC50 of 0.93 uM, approximately 2-fold more active than the racemate FQI-1. |
| PC-61994 |
TK216
EWS-FLI1 inhibitor
|
TK216 is a first in class, small molecule that directly binds EWS-FLI1 inhibiting the biological activity of ETS-family transcription factor oncoproteins and is currently under clinical investigation against Ewing sarcoma.. |
| PC-61918 |
Cyclocreatine Phosphate
Creatine kinase inhibitor
|
Cyclocreatine Phosphate (AM 285) is an analog of the creatine kinase CKMT1 substrate creatine and inhibitor of the creatine biosynthesis pathway. |
