| Cat. No. |
Product Name |
Information |
| PC-21277 |
MSN-CD44 inhibitor 1
CD44-MSN inhibitor
|
MSN-CD44 inhibitor 1 is a small molecule FERM domain protein-protein interaction inhibitor for moesin (MSN) and CD44 with SPR KD of 4.2 uM, is a potent inhibitor of CD44-MSN interaction in live cells with IC50 of 600 nM. |
| PC-21265 |
Feeblin
IRF5 inhibitor
|
Feeblin (SLC15A4 inhibitor C5) is a small molecule inhibitor of the proinflammatory TLR7/8/9-IRF5 pathway (IC50=1.6 uM) by disrupting the SLC15A4-TASL adapter module, Feeblin is an IRF5 pathway-specific inhibitor. |
| PC-21240 |
NOX-6-7
GPR132 agonist
|
NOX-6-7 is a potent, selective GPR132 agonist with EC50 of 44 nM. |
| PC-21239 |
NOX-6-18
GPR132 inhibitor
|
NOX-6-18 is a potent, selective GPR132 antagonist with IC50 of 17 nM. |
| PC-21213 |
YL-365
GPR34 inhibitor
|
YL-365 (YL365) is a highly potent, selective and competitive antagonist of GPR34. |
| PC-21184 |
UGT8 inhibitor 19
UGT8 inhibitor
|
UGT8 inhibitor 19 (UGT8-IN-1) is a highly potent, selective and orally active ceramide galactosyltransferase enzyme UGT8 inhibitor with IC50 of 0.2 nM. |
| PC-21174 |
Kisspeptin 234
GPR54 inhibitor
|
Kisspeptin 234 (Peptide 234, P234) is a potent kisspeptin receptor (KISS1, GPR54) antagonist antagonist with binding IC50 of 2.7 nM in competition with 125I-kisspeptin-10, blocks the stimulatory effects of kisspeptin on hypothalamus-pituitary-gonadal (HPG) axis. |
| PC-21150 |
ST2 inhibitor XY52
ST2 inhibitor
|
ST2 inhibitor XY52 is a specific small molecule inhibitor of soluble suppression of tumorigenesis-2 factor (ST2) with IC5 of 5.68 and 4.59 uM in ST2/IL-33 AlphaLISA and HEK-Blue reporter assays, repsectively. |
| PC-21142 |
(3S) ALG-05
TILs inhibitor
|
(3S) ALG-05 is a potent pan-inhibitor of gut microbia tryptophan-indole-lyases (TILs, E.C. 4.1.99.1), exhibits inhibitory activity across TILs with Ki of 7-11 uM. |
| PC-21113 |
VJDT
TREM1 inhibitor
|
VJDT (TREM1 inhibitor) is a novel small molecule inhibitor of triggering receptor expressed on myeloid cell 1 (TREM1), effectively blocks TREM1 signaling. |
| PC-21099 |
DSHN-OMe
NR0B2 agonist
|
DSHN-OMe (DSHN methyl ester) is a small molecule modulator of NR0B2, effectively reduces induction of LXR target gene ABCA1 by GW3965 (1 uM) in BMDMs with IC50 of 3.8 uM, reduces regulatory T cell expansion and impede breast cancer progression. |
| PC-21097 |
PSB-KK1415
GPR18 agonist
|
PSB-KK1415 is a selective GPR18 agonist with EC50 of 19.1 nM (hGPR18) in β-arrestin recruitment assays, shows no activity against GPR55. |
