| Cat. No. |
Product Name |
Information |
| PC-27442 |
FSG67
GPAT inhibitor
|
FSG67 is a small molecule mitochondrial glycerol-3-phosphate acyltransferase (mitochondrial GPAT, GPAM) inhibitor with IC50 30.2 μM for total mitochondrial GPAT and 42.1 μM for GPAT1. |
| PC-27404 |
Alcedaplin
APOL1 inhibitor
|
Alcedaplin (MZE829) is a small molecule inhibitor of apolipoprotein L1 (APOL1) function, blocks APOL1 pore function and ameliorate manifestations of APOL1-mediated kidney disease (AMKD). |
| PC-27294 |
LRPPRC inhibitor 3o
LRPPRC inhibitor
|
LRPPRC inhibitor 3o (LRPPRC-IN-1) is a potent small molecule inhibitor of Leucine-rich pentatricopeptide repeat containing (LRPPRC) with IC50 of <5 uM (92% inhibition at 6.25 uM), induces robust LRPPRC degradation. |
| PC-27293 |
FKA-9i
LRPPRC-YBX1-RPN1 inhibitor
|
FKA-9i is a potent broad-spectrum anticancer agent, directly binds to leucine-rich PPR motif-containing protein (LRPPRC), Y-box binding protein 1 (YBX1), and ribophorin I (RPN1) with 7.387 μM, 26.82 μM, and 16.52 μM, respectively, reducing their interactions and stability. |
| PC-27273 |
PBITE-1
ERG PNT domain binder
|
PBITE-1 is a small molecule that selectively binds ERG N-terminal Pointed (PNT) domain with Kd of 264 uM in BLI assays, directly engages ERG, selectively inhibits proliferation and invasion, and induces apoptosis in ERG-driven prostate and hematologic malignancies. |
| PC-27270 |
XL20
TDP-43 inhibitor
|
XL20 is a brain-penetrant small molecule targeting the TDP-43 conserved α-helical region spanning residues 320-340 (conserved region, CR) to suppress neurotoxicity, binds to full-length TDP-43 and CR peptide with SPR KD of 10.4 uM and 7.84 uM. |
| PC-27237 |
CD73 inhibitor Compound 73
CD73 inhibitor
|
CD73 inhibitor Compound 73 (CD73-IN-5) is a potent and selective non-nucleotide small molecule inhibitor of CD73 (ecto-5′-nucleotidase, eN) with IC50 of 12 nM. |
| PC-27212 |
A2ti-2
S100A10-ANXA2 inhibitor
|
A2ti-2 (S100A10-ANXA2 heterotetramer inhibitor-2) is a specific small molecule Annexin A2 (ANXA2) inhibitor, inhibits Annexin A2-S100A10 protein interaction with IC50 of 230 nM (Annexin A2/S100A10 heterotetramer (A2t)), blocks HPV16 infection and entry into HeLa cells. |
| PC-27202 |
SGM-3
Striga germination inhibitor, ShHTL7 inhibitor
|
Striga germination modulator-3 (SGM-3) is a potent, selective germination inhibitor for Striga hermonthica, selectively binds to ShHTL7 and shows inhibitory activity against YLG hydrolysis by ShHTL7 with IC50 of 2.3 uM. |
| PC-27201 |
KK023-N1
Striga germination inhibitor, ShHTL7 inhibitor
|
KK023-N1 is a potent, specific Striga germination inhibitor, blocks the hydrolysis activity of S. hermonthica HYPO-SENSITIVE TO LIGHT 7 (ShHTL7) with IC50 of 1.78 uM, does not affect rice (Oryza sativa) SL receptor DWARF14 (OsD14). |
| PC-27135 |
Galinex
GPR17 agonist
|
Galinex is a highly potent, selective GPR17 agonist with EC50 of 0.64 nM, Emax=127.8% in [35S]GTPγS functional assays in membranes from 1321N1 cells transfected with human GPR17. |
| PC-27105 |
A2ti-1
S100A10-ANXA2 inhibitor
|
A2ti-1 (S100A10-ANXA2 heterotetramer inhibitor-1) is a specific small molecule Annexin A2 (ANXA2) inhibitor, inhibits Annexin A2-S100A10 protein interaction with IC50 of 24 uM (Annexin A2/S100A10 heterotetramer (A2t)). |
