| Cat. No. |
Product Name |
Information |
| PC-21664 |
AD-8007
ACSS2 inhibitor
|
AD-8007 is a potent, brain permeable human Acetyl-CoA synthetase 2 (ACSS2) inhibitor with IC50 of 0.89 uM, a key metabolic enzyme involved in regulating fatty acid synthesis and protein acetylation in tumor cells. |
| PC-21663 |
AD-5584
ACSS2 inhibitor
|
AD-5584 is a potent, brain permeable human Acetyl-CoA synthetase 2 (ACSS2) inhibitor with IC50 of 0.86 uM, a key metabolic enzyme involved in regulating fatty acid synthesis and protein acetylation in tumor cells. |
| PC-21630 |
QP5038
QPCTL inhibitor
|
QP5038 is a potent inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with IC50 of 3.8 nM, shows promising in vitro and in vivo anti-tumor efficacies. |
| PC-21628 |
RBS-10
NQO1 inhibitor
|
RBS-10 is a small molecule that shows preferential cytotoxicity against cells pan-resistant to degraders, acts as a prodrug bioactivated by the oxidoreductase enzyme NQO1. |
| PC-21626 |
PQ912
Glutaminyl cyclase inhibitor
|
Varoglutamstat (PQ912) is a potent glutaminyl cyclase (QC) inhibitor with Ki values of 20-65 nM for human, rat, and mouse QC activity. |
| PC-21625 |
BK697
FIRΔexon2 inhibitor
|
BK697 is a small molecule targeting FIRΔexon2, potentially interacts with FIRΔexon2, significantly suppresses the FIRΔexon2 expression and inhibits tumor cell growth and several rRNA expressions. |
| PC-21576 |
PCC0105003
MARK inhibitor
|
PCC0105003 is a small molecule microtubule affinity-regulating kinases (MARKs) inhibitor with IC50 of 3.0, 2.0, 2.67 and 2.67 nM for MARK1, 2, 3 and 4 repectively. |
| PC-21575 |
BiTud
TDRD3 inhibitor
|
BiTud is a bivalent inhibitor against TDRD3 with binding Kd of 6 uM for tandem Tudor chimera, blocks the recruitment of TDRD3 by the two methylated arginines of G3BP1, suppress the phase separation of methylated G3BP1, TDRD3, and RNAs, and in turn inhibits the stress granule growth in cells. |
| PC-21523 |
DS68591889
PTDSS1 inhibitor
|
DS68591889 (PTDSS1i) is a potent, selective phosphatidylserine synthase 1 (PTDSS1) inhibitor, highly sellective over PTDSS2, induces phospholipid imbalance in a wide range of cancer cells. |
| PC-21516 |
HJ445A
Myoferlin inhibitor
|
HJ445A is a highly potent, selective myoferlin (MYOF) inhibitor, binds to MYOF-C2D domain with KD value of 0.17 uM. |
| PC-21430 |
WDR91-IN-1
WDR91 inhibitor
|
WDR91-IN-1 is a small molecule ligand of WD40 repeat-containing protein 91 (WDR91) with SPR KD value of 6 uM. |
| PC-21417 |
HQY436
CPSF3 inhibitor
|
HQY436 is a specific, orally bioavailable inhibitor of pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3 (CPSF3) with binding IC50 of 0.15 uM, exhibits potent antitumor activity. |
