| Cat. No. |
Product Name |
Information |
| PC-24222 |
I3MT-3
3MST inhibitor
|
I3MT-3 (HMPSNE, 3MST inhibitor 3) is a potent, selective, cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) with IC50 of 2.7 uM. |
| PC-24167 |
Pariceract
GCase activator
|
Pariceract (LTI-291) is an allosteric, CNS-penetrable glucosylceramidase beta (glucocerebrosidase, GCase) activator. |
| PC-24123 |
Dencatistat
CTPS1 inhibitor
|
Dencatistat (STP938) is a potent, orally bioavailable, selective inhibitor of cytidine triphosphate synthase 1 (CTPS1) with IC50 of <100 nM, specifically blocks cell proliferation of the hematological cancers. |
| PC-24108 |
LIBX-A401
ACSL4 inhibitor
|
LIBX-A401 is a potent, selective inhibitor of Acyl-coenzyme A synthetase long-chain family member 4 (ACSL4) with IC50 of 0.38 uM, MST KD of 0.72 uM, with high selectivity over ACSL3 (IC50>50 uM), protects cells from ferroptosis. |
| PC-24061 |
(R)-dMGer
KAI2 agonist
|
(+)-dMGer ((R)-dMGer) is a potent agonist of Karrikin Insensitive 2 (KAI2), inhibits KAI2 hydrolytic activity with IC50 of 0.16 uM. |
| PC-24060 |
dMGer
KAI2 agonist
|
dMGer (DesmethylGerminone) is a potent and selective HTL/KAI2 (KAI2, Karrikin Insensitive 2) agonist, inhibits KAI2-dependent dMYLG hydrolysis with IC50 of 46 nM. |
| PC-24039 |
RUN-47
NRF1 activator
|
RUN-47 is a small-molecule activator of NRF1 with EC50 of 6.43 uM in 3xPSMA4-ARE-LUC reporter assays, specifically activates NRF1 pathway. |
| PC-23950 |
PKRA7
Prokineticin 2 antagonist
|
PKRA7 (PKRA83) is a potent prokineticin receptor 2 (PKR2, PROK2, PK2) antagonist, potently inhibits PK2 receptors with IC50 of 5.0 and 8.2 nM for PKR1 and PKR2, respectively. |
| PC-23917 |
JH-ENT-01
ENT1 inhibitor
|
JH-ENT-01 is a potent, specific inhibitor of the equilibrative nucleoside transporter subtype 1 (ENT1) with Ki of 92.7 nM, shows good selectivity for hENT1 over hENT2. |
| PC-23912 |
TN2008
SRSF1 inhibitor
|
TN2008 is an effective serine arginine-rich splicing factor 1 (SRSF1) inhibitor with IC50 of 144 uM, exhibits high affinity for recombinant SRSF1 with Kd of 5.13 uM in SPR assays. |
| PC-23857 |
VK-2019
EBNA1 inhibitor
|
VK-2019 is a selective small molecule inhibitor of Epstein-Barr virus Nuclear Antigen 1 (EBNA1), reduces EBV genome copy number and viral gene expression in EBV-positive nasopharyngeal carcinoma. |
| PC-23850 |
ALT-007
Serine palmitoyltransferase inhibitor
|
ALT-007 is a potent, selective and orally bioavailable inhibitor of serine palmitoyltransferase (SPT) with enzyme IC50 of 0.54 nM. |
