| Cat. No. |
Product Name |
Information |
| PC-49675 |
DS07551382
PTDSS1 inhibitor
|
DS07551382 (DS 07551382) is potent, selective and orally active PTDSS1 (phosphatidylserine synthetase 1), suppresses phosphatidylserine (PS) production activity of PTDSS1 (IC50=100 nM) in cell-free assays, but not that of PTDSS2. |
| PC-49648 |
FK3453
TSLP inhibitor
|
FK3453 (FK 3453) is a novel inhibitor of thymic stromal lymphopoietin (TSLP) production, reduces both TSLP protein levels and mRNA levels both in vitro and in vivo. |
| PC-49633 |
BI-3231
HSD17B13 inhibitor
|
BI-3231 (BI 3231) is a potent, selective HSD17B13 (hydroxysteroid 17β-dehydrogenase 13) inhibitor with enzyme IC50 of 1 and 14 nM for human and mouse HSD17B13, respectively. |
| PC-49632 |
BI-0955
HSD17B13 inhibitor
|
BI-0955 is an inactive HSD17B13 control compound for BI-3231. |
| PC-49628 |
PKR inhibitor C16
PKR inhibitor
|
PKR inhibitor C16 (GW506033X) is a specific small molecule inhibitor of double-stranded RNA-dependent protein kinase (PKR). |
| PC-49621 |
JYQ-88
PARK7 (DJ-1) inhibitor
|
JYQ-88 is a potent, selective and covalent PARK7 inhibitor with IC50 of 0.13 uM in DiFMUAc assays, 100-fold selectivity over UCHL1 (PARK5, IC50=11.1 uM), covalently modifies the active site Cys106. |
| PC-49591 |
DDIT
Hyaluronan synthase inhibitor
|
DDIT is a potent, non-toxic inhibitor of hyaluronan synthesis via targeting hyaluronan synthase (HAS), significantly suppresses the aggressiveness of triple-negative breast cancer cells grown in tissue culture. |
| PC-49589 |
ARUK2001607
PI5P4Kγ inhibitor
|
ARUK2001607 is a potent, selective and brain penetrant PI5P4Kγ inhibitor with binding KD of 7.1 nM, pIC50 of 7.1 (PI5P4Kγ+). |
| PC-49548 |
DS55980254
PTDSS1 inhibitor
|
DS55980254 (DS 55980254) is potent, selective and orally active PTDSS1 (phosphatidylserine synthetase 1) inhibitor, suppresses phosphatidylserine (PS) production activity of PTDSS1 (IC50=100 nM) in cell-free assays, but not that of PTDSS2. |
| PC-49527 |
SEN177
Glutaminyl cyclase inhibitor
|
SEN177 (SEN-177) is a highly potent human glutaminyl cyclase (hQC) inhibitor Ki value of 20 nM. |
| PC-49503 |
LMTK3 inhibitor C36
LMTK3 inhibitor
|
LMTK3 inhibitor C36 is a highly selective, ATP-competitive inhibitor of lemur tyrosine kinase 3 (LMTK3) with IC50 of 100 nM in in vitro kinase assays and MST binding Kd of 1.87 uM. |
| PC-49470 |
MO-I-1182
ASPH inhibitor
|
MO-I-1182 is a small molecule inhibitor of aspartate beta-hydroxylase (ASPH), suppresses cholangiocarcinoma metastasis. |
