| Cat. No. |
Product Name |
Information |
| PC-72077 |
NCGC00108248
Mir155 inhibitor
|
NCGC00108248 is small molecule inhibitor of Mir155 reporter, dose-dependently inhibits Mir155 reporter expression with EC50 of 2.2 uM. |
| PC-72076 |
ClpXP inhibitor 334
ClpXP inhibitor
|
ClpXP inhibitor 334 is a small molecule inhibitor of the mitochondrial ClpXP protease with anti-cancer activity. |
| PC-72071 |
hNPR1 inhibitor JS-11
NPR1 inhibitor
|
hNPR1 inhibitor JS-11 is a selective small-molecule inhibitor of NPPB receptor NPR1 (natriuretic peptide receptor 1), does not inhibit adenylate cyclases (ACs) family of enzymes. |
| PC-72067 |
ALC-0159
PEGylated lipid
|
ALC-0159 is a PEGylated lipid which has been used to form lipid nanoparticles for delivery of RNA. ALC-0159 is one of the components in the BNT162b2 vaccine against SARS-CoV-2 in addition to ALC-0315, DSPC, and cholesterol. |
| PC-72066 |
SAR439883
PKR inhibitor
|
SAR439883 (SAR 439883) is a novel potent, selective, orally active PKR inhibitor with IC50 of 0.68/0.69 uM against hPKR/mPKR, respectively. |
| PC-72048 |
YE6144
IRF5 inhibitor
|
YE6144 (YE 6144) is a specific small molecule inhibitor of transcription factor IFN regulatory factor 5 (IRF5), selectively suppresses IRF5 activity through inhibition of IRF5 phosphorylation. |
| PC-72047 |
IRF5 inhibitor N5-1
IRF5 inhibitor
|
IRF5 inhibitor N5-1 (PRRVRLK) is a cell permeable, IRF5 peptide mimetic that selectively bind to and stabilizes the inactive IRF5 monomer with KD of 98.8 nM. |
| PC-72031 |
ARH3 inhibitor 26
ARH3 inhibitor
|
ARH3 inhibitor 26 (AI26) is a small molecule ADP-ribosylhydrolase ARH3 inhibitor that binds to the catalytic pocket of ARH3 and inhibits the enzymatic activity of ARH3 with IC50 of 2.41 uM in vitro. |
| PC-72028 |
NIO-1
OCT1 inhibitor
|
NIO-1 (Novel inhibitor of OCT1) is a novel small molecule inhibitor of Octamer transcription factor OCT1, inhibits OCT1 activation with IC50 of 0.11 uM. |
| PC-72024 |
SU0268
OGG1 inhibitor
|
SU0268 (SU 0268) is a potent, selective, noncovalent inhibitor DNA repair enzyme 8-oxoguanine DNA glycosylase (OGG1) with IC50 of 59 nM. |
| PC-72022 |
BIM5078
HNF4α antagonist
|
BIM5078 (BIM-5078) is a potent synthetic HNF4α antagonist, binds to HNF4α with high affinity (EC50=11.9 nM) and modulates HNF4α target genes and metabolic processes controlled by HNF4α. |
| PC-72021 |
BI6015
HNF4α antagonist
|
BI6015 (BI-6015) is a potent synthetic HNF4α antagonist, binds to HNF4α with high affinity and modulates HNF4α target genes and metabolic processes controlled by HNF4α. |
