| Cat. No. |
Product Name |
Information |
| PC-60222 |
CK-2127107
|
CK-2127107(CK-107, Reldesemtiv) is a novel orally active fast skeletal troponin activator, selectively activates fast skeletal myofibrils with EC50 of 3.4 uM. |
| PC-60193 |
2-D08
UBC9 SUMOylation inhibitor
|
2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation, inhibits transcriptional expressions of SUMO1/2 and Ubc9. |
| PC-60184 |
Shield-1
FKBP ligand
|
Shield-1 is a cell-permeable FKBP ligand that is designed to protect an otherwise unstable protein domain from degradation. |
| PC-70005 |
Gue-1654
OXE-R inhibitor
|
Gue-1654 (GUE 1654) is a small-molecule that inhibits Gβγ but not Gα signaling triggered upon activation of Gα(i)-βγ by the chemoattractant receptor OXE-R (Oxoeicosanoid receptor) in both recombinant and human primary cells. |
| PC-70001 |
C1632
|
C1632 (Lin28-IN-1632) is a small molecule inhibitor of RNA binding protein Lin28 that blocks the Lin28/let-7 interaction, rescues let-7 processing and function in Lin28-expressing cancer cells. |
| PC-60018 |
RU-521
cGAS inhibitor
|
RU-521 (RU.521, RU-320521) is a potent, selective cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 36.2 nM. |
| PC-42914 |
PFK-158
PFKFB3 inhibitor
|
PFK-158 is the first potent, selective and competitive small molecule inhibitor of PFKFB3 with IC50 of 137 nM, inhibits glycolysis, induces apoptosis and autophagy. |
| PC-45661 |
MCB-613
|
MCB-613 is a potent steroid receptor coactivator (SRC1, SRC2 and SRC3) stimulator. |
| PC-45685 |
Emixustat hydrochloride
|
Emixustat (ACU-4429) is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM. |
| PC-45684 |
Emixustat
RPE65 inhibitor
|
Emixustat (ACU-4429) is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM. |
| PC-45840 |
Azeliragon
RAGE inhibitor
|
Azeliragon (TTP-488;PF-04494700) is an orally bioavailable small molecule inhibitor of RAGE, inhibits sRAGE from binding to RAGE ligands, S100b, amphoterin and carboxymethyl-lysine. |
| PC-45179 |
Deferasirox
Iron chelator
|
Deferasirox is an oral iron chelator that used to reduce chronic iron overload, also induces apoptosis in myeloid leukemia cells by targeting caspase. |
