| Cat. No. |
Product Name |
Information |
| PC-45522 |
GBT-440
|
GBT-440 (Voxelotor) is a new potent allosteric effector of sickle cell hemoglobin. |
| PC-42293 |
EC330
|
EC330 (EC-330, EC 330) is a first-in-class LIF (leukemia inhibitory factor) inhibitor. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
|
TPEN (LIN28 inhibitor TPEN) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-22713 |
Bongkrekic acid
Mitochondrial toxin
|
Bongkrekic acid is a specific small molecule inhibitor of the adenine nucleotide translocase of mitochondria and mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans, inhibits ADP/ATP transport. |
| PC-22708 |
Necrox-7
HMGB1 inhibitor, Necrosis inhibitor
|
NecroX-7 (NecX, NecroX 7) is a small molecule necrosis inhibitor by inhibiting high-mobility group box 1 protein (HMGB1) release. |
| PC-22695 |
LH1753
L-cystine crystallization inhibitor
|
LH1753 is an orally bioavailable inhibitor of L-cystine crystallization for cystinuria, prevents stone formation effectively in the Slc3a1-knockout mouse model. |
| PC-22694 |
DS21360717
FER kinase inhibitor
|
DS21360717 is a highly potent inhibitor of feline sarcoma-related (FER) tyrosine kinase tyrosine kinase with IC50 of 0.49 nM, shows in vivo antitumor efficacy. |
| PC-22693 |
DS08701581
FER kinase inhibitor
|
DS08701581 is a highly potent inhibitor of feline sarcoma-related (FER) tyrosine kinase with IC50 of 0.32 nM, shows in vivo antitumor efficacy. |
| PC-22686 |
NSI-189 phosphate
Neurogenic compound
|
NSI-189 phosphate is an orally active benzylpiperizine-aminiopyridine compound with neurogenic activity, stimulates neurogenesis of human hippocampus-derived neural stem cells in vitro and stimulates neurogenesis in murine hippocampus in vivo. |
| PC-22685 |
NSI-189
Neurogenic compound
|
NSI-189 is an orally active benzylpiperizine-aminiopyridine compound with neurogenic activity, stimulates neurogenesis of human hippocampus-derived neural stem cells in vitro and stimulates neurogenesis in murine hippocampus in vivo. |
