| Cat. No. |
Product Name |
Information |
| PC-22842 |
SD-066-4
ZDHHC20 inhibitor
|
SD-066-4 is a selective inhibitor of S-acyltransferase ZDHHC20 (Zinc Finger DHHC-Type Palmitoyltransferase 20), inhibits EGFR S-acylation at concentrations as low as 1 uM. |
| PC-22812 |
EHD4 inhibitor MS1
EHD4 inhibitor
|
EHD4 inhibitor MS1 is a small molecule inhibitor of Eps15 Homology Domain Protein 4 (EHD4) with IC50 of 0.92 uM, inhibits Eps15 EHD4's liposome-stimulated ATPase activity. |
| PC-22799 |
BCAT1 inhibitor 2
BCAT1 inhibitor
|
BCAT1 inhibitor 2 (Bi2) is a specific inhibitor of cytosolic branched-chain aminotransferase (BCATc, BCAT1) with IC50 of 0.2/ 0.8 uM for rat/human BCATc respectively, weakly inhibits rat mitochondrial isoenzyme rBCATm. |
| PC-22793 |
BIIB-TTBKi
TTBK inhibitor
|
BIIB-TTBK1i is a potent selective inhibitor of CNS-specific tau kinase Tau Tubulin Kinase 1 (TTBK1) with IC50 of 9.5 nM in recombinant kinase assay, inhibits tau phosphorylation at S422 (pS422) with IC50 of 9.75 nM in cell-based assays. |
| PC-22792 |
TTBK1 inhibitor 31
TTBK inhibitor
|
TTBK1 inhibitor 31 is a potent, selective and CNS-penetrant Tau Tubulin Kinase 1 (TTBK1) inhibitor with IC50 of 2.7 nM, inhibits tau phosphorylation at the disease-relevant Ser 422 epitope. |
| PC-22766 |
Pertussis Toxin
Gi protein inhibitor
|
Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, inhibits G protein-coupled receptor (GPR) signaling through Gi proteins. |
| PC-22760 |
AS1411
Nucleolin inhibitor
|
AS1411 is a quadruplex-forming oligonucleotide aptamer that targets nucleolin, inhibits cancer cell proliferation. |
| PC-22755 |
GCS-12
NKT cell agonist
|
GCS-12 is a highly potent αGalCer sulfonamide analogue as natural killer T (NKT) cell agonist, enhances interaction of the glycolipid/CD1d complex, exhibits selectivity for the induction of IFN-γ over IL-4, shows potent antitumor activities. |
| PC-22754 |
GCS-11
NKT cell agonist
|
GCS-11 is a highly potent αGalCer sulfonamide analogue as natural killer T (NKT) cell agonist, enhances interaction of the glycolipid/CD1d complex, exhibits selectivity for the induction of IFN-γ over IL-4, shows potent antitumor activities. |
| PC-22713 |
Bongkrekic acid
Mitochondrial toxin
|
Bongkrekic acid is a specific small molecule inhibitor of the adenine nucleotide translocase of mitochondria and mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans, inhibits ADP/ATP transport. |
| PC-22695 |
LH1753
L-cystine crystallization inhibitor
|
LH1753 is an orally bioavailable inhibitor of L-cystine crystallization for cystinuria, prevents stone formation effectively in the Slc3a1-knockout mouse model. |
| PC-22694 |
DS21360717
FER kinase inhibitor
|
DS21360717 is a highly potent inhibitor of feline sarcoma-related (FER) tyrosine kinase tyrosine kinase with IC50 of 0.49 nM, shows in vivo antitumor efficacy. |
