| Cat. No. |
Product Name |
Information |
| PC-24358 |
JM-20
Neuroprotective agent
|
JM-20 is a benzodiazepine–dihydropyridine hybrid molecule, preventsPC-12 cell death induced either by glutamate, hydrogen peroxide or KCN-mediated chemical hypoxia, a multi-target neuroprotective agent. |
| PC-24321 |
SBDA
RCC2 inhibitor
|
SBDA is a small molecule inhibitor of RCC2 (TD-60) active pocket and specifically blocks RCC2 lactylation, inhibits breast cancer cell proliferation. |
| PC-24318 |
LPHN2 inhibitor D11
LPHN2 inhibitor
|
LPHN2 inhibitor D11 is a reversible and selective inhibitor of mechanosensitive GPCR latrophilin 2 (LPHN2, ADGRL2), inhibits mechanosensitivity of LPHN2 in HEK293 cells with IC50 of 20 nM. |
| PC-24316 |
Calycosin
PANoptosis inhibitor
|
Calycosin is a flavonoid compound derived from the root of Astragalus, alleviates ischemic stroke by inhibiting PANoptosis. |
| PC-24311 |
2-AAPA
Glutathione reductase inhibitor
|
2-AAPA is an irreversible inhibitor of glutathione reductase (GR) with Ki of 56 uM (yeast GR), induces ferroptosis in A549 cells, induces microtubule S-glutathionylation. |
| PC-24310 |
NFS1 inhibitor Compound 53
NFS1 inhibitor
|
NFS1 inhibitor Compound 53 is the first potent, selective inhibitor of human cysteine desulfurase (NFS1) with IC50 of 40.5 uM and Ki of 6.4 uM. |
| PC-24293 |
HypoxyStat
Hypoxia inducer
|
HypoxyStat is a small molecule that increase oxygen-hemoglobin binding affinity cause tissue hypoxia, binds hemoglobin, induces systemic hypoxia in mice breathing normoxic (21% O2) air. |
| PC-24282 |
BKT300
PRC1 inhibitor
|
BKT300 is a small molecule inhibitor of leukemic cell migration and survival by targeting the PRC1 pathways, efficiently and specifically binds protein regulator of cytokinesis 1 (PRC1) with SPR Kd of 28.3 nM. |
| PC-24261 |
SARM1 inhibitor NB-7
SARM1 inhibitor
|
SARM1 inhibitor NB-7 is a potent, selective and uncompetitive inhibitor of the nicotinamide adenine dinucleotide (NAD) hydrolase SARM1 with biochemical IC50 of 0.025 uM, and IC50 of 0.008 uM in SARM-induced cell-death rescue assays. |
| PC-24260 |
SARM1 inhibitor 7
SARM1 inhibitor
|
SARM1 inhibitor 7 is a potent, selective sterile alpha and TIR Motif Containing 1 (SARM1) inhibitor with biochemical IC50 of 0.3 uM (hSARM1). |
| PC-24247 |
ACUPA TFA
PSMA inhibitor
|
ACUPA TFA is a potent prostate-specific membrane antigen (PSMA, GCPII) antagonist with Ki of 44.3 nM. |
| PC-24246 |
ACUPA
PSMA inhibitor
|
ACUPA is a potent prostate-specific membrane antigen (PSMA, GCPII) antagonist with Ki of 44.3 nM. |
