Catalog No.: PC-42064Not For Human Use, Lab Use Only.
CD73-IN-1 (eN-IN-1, N-[(4-Aminophenyl)methyl]adenosine) is an α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 29 nM for rat recombinant eN.
CD73-IN-1 (eN-IN-1, N-[(4-Aminophenyl)methyl]adenosine) is an α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 29 nM for rat recombinant eN.
CD73-IN-1 also exhibits dual-action properties toward both A2AR and equilibrative nucleoside transporter 1 (ENT1) with Ki of 27.7 uM and 6.51 nM.
Physicochemical Properties
M.Wt
372.3785
Formula
C17H20N6O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Adenosine, N-[(4-aminophenyl)methyl]-
References
1. Bhattarai S, et al. J Med Chem. 2015 Aug 13;58(15):6248-63.
2. Chen JB, et al. ChemMedChem. 2011 Aug 1;6(8):1390-400.
