| Cat. No. |
Product Name |
Information |
| PC-72031 |
ARH3 inhibitor 26
ARH3 inhibitor
|
ARH3 inhibitor 26 (AI26) is a small molecule ADP-ribosylhydrolase ARH3 inhibitor that binds to the catalytic pocket of ARH3 and inhibits the enzymatic activity of ARH3 with IC50 of 2.41 uM in vitro. |
| PC-72020 |
ART558
Polθ inhibitor
|
ART558 (ART-558) is a highly potent, selective, allosteric inhibitor of the polymerase function of DNA polymerase Polθ with IC50 of 7.9 nM. |
| PC-72015 |
INI-43
Kpnβ1 inhibitor
|
INI-43 (Inhibitor of Nuclear Import-43, ZINC20547783) is a small molecule that bind nuclear import receptor Karyopherin beta 1 (Kpnβ1), inhibits Kpnβ1-mediated nuclear import with anti-cancer activity. |
| PC-38337 |
CH24H inhibitor 17
CH24H inhibitor
|
CH24H inhibitor 17 is a potent, highly selective, BBB permeable inhibitor of Cholesterol 24-hydroxylase (CH24H/CYP46A1) with IC50 of 8.5 nM. |
| PC-38323 |
DMT1 inhibitor 18g
DMT1 inhibitor
|
DMT1 inhibitor 18g is the most potent inhibitor of divalent metal transporter 1 (DMT1) with IC50 of 20 nM in calcein fluorescence assay.. |
| PC-38320 |
msR4M-L1
MIF inhibitor
|
msR4M-L1 is a chemokine-selective CXCR4 ectodomain mimic that selectively binds to MIF (KD<40 nM) but not CXCL12 (>140-fold selectivity). |
| PC-38301 |
PRGL493
ACSL4 inhibitor
|
PRGL493 (PRGL 493) is a potent selective inhibitor of Acyl-CoA synthetase 4 (ACSL4). |
| PC-38288 |
Apostatin-1
TRADD inhibitor
|
Apostatin-1 is a small molecule that binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N). |
| PC-38287 |
ICCB-19
TRADD inhibitor
|
ICCB-19 is a small molecule that binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N). |
| PC-38284 |
LDC7559
PFKL activator
|
LDC7559 is a small molecule that efficiently blocks NET formation and GSDMD-mediated pyroptotic cell death in human cells, also is an inhibitor of NOX2-dependent NETosis. |
| PC-38283 |
PFKL activator NA-11
PFKL activator
|
PFKL activator NA-11 is a small-molecule, selective PFKL activator, inhibits the NOX2-dependent oxidative burst in neutrophils by activating the glycolytic enzyme phosphofructokinase-1 liver type (PFKL). |
| PC-38280 |
ENPP1 inhibitor 32
ENPP1 inhibitor
|
ENPP1 inhibitor 32 is a potent, cell-impermeable small molecule inhibitor of ENPP1 with Ki of < 2 nM. |
