| Cat. No. |
Product Name |
Information |
| PC-62427 |
IMM-01
|
IMM-01 is a small molecule agonist of mammalian Diaphanous (mDia)-related formins that disrupts diaphanous inhibitory domain (DID) and diaphanous autoregulatory domain (DAD) interaction with IC50 of 140 nM. |
| PC-62412 |
PDD 00017273
|
PDD 00017273 (PDDX-001) is the first-in-class, selective inhibitor of poly(ADP-ribose) glycohydrolase (PARG) with Kd, biochemical EC50 of 1.45 nM, 26 nM. |
| PC-62403 |
CI-976
|
CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM. |
| PC-62387 |
OSMI-1
O-GlcNAc transferase inhibitor
|
OSMI-1 is a cell-permeable, small molecule O-GlcNAc transferase (OGT) inhibitor with IC50 of 2.7 uM. |
| PC-62382 |
RH01687
|
RH01687 is a small molecule that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death. |
| PC-62379 |
BCI-137
|
BCI-137 is a chemical compound able to compete with Argonaute 2 miRNAs binding, binds to Ago2 with Kd of 126 uM. |
| PC-62368 |
BRD9092
ROS inducer
|
BRD9092 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer.. |
| PC-62367 |
BRD5459
ROS inducer
|
BRD5459 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer.. |
| PC-62363 |
MN30
APOBEC3G inhibitor
|
MN30 (Methyl-3,4-dephostatin, APOBEC3G inhibitor MN30) is a first-in-class, selectve small molecule inhibitor of the single-strand DNA cytosine deaminase APOBEC3G with IC50 of 9.1 uM. |
| PC-62361 |
Aurintricarboxylic acid
|
NSC4056 (Aurintricarboxylic acid) is a potent, bioactive inhibitor of cystathionine γ-lyase (CSE) with IC5 of 0.6 uM, also is a selective inhibitor of the TWEAK-Fn14 signaling pathway. |
| PC-62342 |
Isobutyl-deoxynyboquinone
NQO1 substrate
|
Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1), produces ROS, and induces cytotoxicity in cancer cells in an NQO1-dependent manner. |
| PC-62316 |
UM-171
|
UM-171 (UM171) is a potent agonist of human hematopoietic stem cell self-renewal, shows 10 to 20 times more potent than UM729 with effective concentrations of 17 to 19 nM. |
