CMP05-7 | Endosomolytic compound | Probechem Biochemicals

Chemical Structure : CMP05-7

CAS No.: 1905413-00-4

CMP05-7 (Endosomolytic compound CMP05-7)

Catalog No.: PC-72948Not For Human Use, Lab Use Only.

CMP05-7 (Endosomolytic compound CMP05-7) is a novel endosomolytic small-molecule compound that exhibits higher transfection efficiency/ability to induce endosomal escape of oligonucleotides (ONs) than current compounds such as chloroquine.

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Biological Activity

Physicochemical Properties

M.Wt	437.932
Formula	C22H24ClN7O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(5-chloro-2-((3-ethoxy-1-(piperidin-4-yl)-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-1H-indole-4-carbonitrile

References

1. Jeremy P Bost, et al. Commun Biol. 2022 Mar 1;5(1):185.

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CMP05-7 (Endosomolytic compound CMP05-7)

Biological Activity

Physicochemical Properties

References

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