| Cat. No. |
Product Name |
Information |
| PC-36026 |
Pyrazinib
|
Pyrazinib (Pyrazinib (P3)) is a pyrazine phenol small molecule drug with anti-angiogenic and anti-metabolic activity in-vivo in zebrafish and in-vitro isogenic models of OAC radioresistance. |
| PC-36024 |
CCI-006
Mitochondrial respiration inhibitor
|
CCI-006 (CCI 006) is a small molecule that inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization, and selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells (MLL-r). |
| PC-36017 |
NEO214
|
NEO214 (NEO-214) is a novel, BBB-permeable rolipram-perillyl alcohol conjugate, shows effectivity against both TMZ-sensitive and TMZ-resistant glioma cells (T98G IC50=40 uM). |
| PC-36016 |
L-291
DDAH1 inhibitor
|
L-291 (DDAH-1 inhibitor L-291) is a selective, competitive DDAH1 inhibitor with IC50 of <25 uM. |
| PC-36015 |
L-257
DDAH1 inhibitor
|
L-257 (DDAH-1 inhibitor L-257) is a selective, competitive DDAH1 inhibitor with IC50 of <25 uM, Ki of 13 uM. |
| PC-36014 |
ZST152
DDAH1 inhibitor
|
ZST152 (ZST-152) is a small molecule DDAH1 (Dimethylarginine dimethylaminohydrolase 1) inhibitor. |
| PC-36013 |
ZST316
DDAH1 inhibitor
|
ZST316 (ZST-316) is a small molecule DDAH1 (Dimethylarginine dimethylaminohydrolase 1) inhibitor with IC50 of 3 uM, Ki of 1 uM. |
| PC-36008 |
BAA473
Pyrin inflammasome activator
|
BAA473 (BAA-473) is a bile acid analogue that functions as the first small molecule activator of the Pyrin inflammasome, induces secretion of IL18 in LPS-primed PBMCs. |
| PC-36002 |
CB-6644
RUVBL1/2 inhibitor
|
CB-6644 (CB6644) is a potent, selective, allosteric, orally bioavailable inhibitor of the ATPase activity of RUVBL1/2 complex with IC50 of 15 nM. |
| PC-36000 |
DB1055
HOXA9/DNA inhibitor
|
DB1055 (DB-1055, DB 1055) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence. |
| PC-35999 |
DB818
HOXA9/DNA inhibitor
|
DB818 (DB-818, DB 818) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence. |
| PC-35997 |
MGR1
ROS inducer
|
MGR1 is a ROS-generating probe that can generate ROS (reactive oxygen species) in different mammalian cells, causes concentration-dependent cell death in HEK293T with IC50 of 5.7 uM. |
