| Cat. No. |
Product Name |
Information |
| PC-36092 |
Fadaltran
α2 adrenoceptor antagonist
|
Fadaltran is an α2-adrenoreceptor antagonist. |
| PC-36087 |
Berotralstat
Plasma kallikrein inhibitor
|
Berotralstat (BCX7353, BCX-7353) is a potent, highly selective, oral plasma kallikrein inhibitor. |
| PC-36076 |
FDI-6
FOXM1 inhibitor
|
FDI-6 (FOXM1 inhibitor FDI6, NCGC00099374) is a small molecule inhibitor of FOXM1 with IC50 of 22.5 uM (FOXM1 DNA binding inhibition). |
| PC-36073 |
AER-271
AQP4 inhibitor
|
AER-271 (AER271) is a selective, small molecule inhibitor of aquaporin-4 (AQP4), the prodrug of AER-270 with enhanced solubility. |
| PC-36065 |
SGC-GAK-1N
|
SGC-GAK-1N is the nagative control compound for SGC-GAK-1, which is a potent, selective, and cell-active inhibitor of cyclin G-associated kinase (GAK).. |
| PC-36053 |
PIN1 inhibitor VS10
Pin1 inhibitor
|
PIN1 inhibitor VS10 is a novel potent small molecule inhibitor of PIN1 (peptidyl-prolyl cis-trans isomerase, NIMA-interacting 1), inhibits human PIN1 isomerization with IC50 of 13.4 uM. |
| PC-36049 |
DFMO
Ornithine decarboxylase inhibitor
|
DFMO (Ornithine Decarboxylase inhibitor DFMO) is an irreversible inhibitor of ornithine decarboxylase (ODC), inhibits polyamine biosynthesis. |
| PC-36048 |
AMXT-1501 tetrahydrochloride
Polyamine transport inhibitor
|
AMXT-1501 tetrahydrochloride (AMXT 1501, AMXT1501) is a novel potent polyamine transport inhibitor, synergistically reduces cell viability in NB cells in combination with DFMO. |
| PC-36047 |
AMXT-1501
Polyamine transport inhibitor
|
AMXT-1501 (AMXT 1501, AMXT1501) is a novel potent polyamine transport inhibitor, synergistically reduces cell viability in NB cells in combination of with DFMO. |
| PC-36026 |
Pyrazinib
|
Pyrazinib (Pyrazinib (P3)) is a pyrazine phenol small molecule drug with anti-angiogenic and anti-metabolic activity in-vivo in zebrafish and in-vitro isogenic models of OAC radioresistance. |
| PC-36024 |
CCI-006
Mitochondrial respiration inhibitor
|
CCI-006 (CCI 006) is a small molecule that inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization, and selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells (MLL-r). |
| PC-36017 |
NEO214
|
NEO214 (NEO-214) is a novel, BBB-permeable rolipram-perillyl alcohol conjugate, shows effectivity against both TMZ-sensitive and TMZ-resistant glioma cells (T98G IC50=40 uM). |
