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UAB126

Chemical Structure : UAB126

CAS No.: 1854907-40-6

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UAB126 (UAB 126)

Catalog No.: PC-38132Not For Human Use, Lab Use Only.

UAB126 (UAB 126) is a novel rexinoid-like small molecule that show positive effects on metabolic syndrome without the known side effects of potent rexinoids.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    UAB126 (UAB 126) is a novel rexinoid-like small molecule that show positive effects on metabolic syndrome without the known side effects of potent rexinoids.
    Oral administration of UAB126 prevents HFD-induced obesity and increases fatty acid oxidation.
    UAB126 modulates genes that are involved in lipolysis and proinflammatory response in WAT, and prevents HFD-induced insulin resistance and HFD-induced hepatic steatosis and hyperlipidemia.
    UAB126 modulates gene expression profiles involved in glucose and lipid metabolism.
    UAB126 suppresses hepatic lipogenic genes, including Srebp-1c, Pparγ2, and Scd1.

    Physicochemical Properties

    M.Wt 274.319
    Formula C19H14O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 1 Month
    Shipping
    Solubility

    Chemical Name/SMILES

    (E)-3-(4-(naphthalen-1-yl)phenyl)acrylic acid

    References

    1. Guang Ren, et al. Diabetes. 2020 Sep;69(9):2003-2016.

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