| Cat. No. |
Product Name |
Information |
| PC-22333 |
ML257
ABHD10 inhibitor
|
ML257 (ABL303) is a selective inhibitor of α,β-hydrolase domain-containing 10 (ABHD10) with IC50 of 21 nM, >59-fold selectivity over 40+ other serine hydrolases. |
| PC-22326 |
E745-0011
TIPE3 inhibitor
|
E745-0011 is a small molecule inhibitor of tumor necrosis factor-α-induced protein 8-like 3 (TNFAIP8L3, TIPE3), exhibits potent anti-tumor activities. |
| PC-22325 |
K784-8160
TIPE3 inhibitor
|
K784-8160 is a small molecule inhibitor of tumor necrosis factor-α-induced protein 8-like 3 (TNFAIP8L3, TIPE3), exhibits potent anti-tumor activities. |
| PC-22324 |
OR51E2 antagonist C80
OR51E2 inhibitor
|
OR51E2 antagonist C80 (Compound 80) is an allosteric antagonist and inverse agonist of olfactory receptor OR51E2 with IC50 of 5.2 uM, acts as a negative allosteric modulator (NAM) by significantly decreasing the agonist efficacy. |
| PC-22305 |
JYQ-164
DJ-1/PARK7 inhibitor
|
JYQ-164 (JYQ164) is a potent, highly selective Parkinson disease protein 7 (PARK7/DJ-1) inhibitor with IC50 of 21 nM, binds covalently and selectively to PARK7 Cys106. |
| PC-22304 |
JYQ-173
DJ-1/PARK7 inhibitor
|
JYQ-173 (JYQ173) is a potent, highly selective Parkinson disease protein 7 (PARK7/DJ-1) inhibitor with IC50 of 19 nM, binds covalently and selectively to PARK7 Cys106. |
| PC-22302 |
α-chlorofluoroacetamide
|
α-chlorofluoroacetamide (CFA) is a novel warhead of targeted covalent inhibitor (TCI), shows high reactivity toward Cys797 of epidermal growth factor receptor (EGFR). |
| PC-22299 |
MTOB sodium
CtBP inhibitor
|
MTOB sodium is a potent C-terminal binding protein (CtBP) inhibitor, inhibits the transactivation activity of CtBP1 and CtBP2. |
| PC-22298 |
CtBP1/BARS inhibitor Comp.11
CtBP1/BARS inhibitor
|
CtBP1/BARS inhibitor Comp.11 is a potent, selective inhibitor targeting the C-terminal-binding protein 1/brefeldin A ADP-ribosylation substrate (CtBP1/BARS), directly binds and inhibits the CtBP1/BARS protein-partners interaction with Kd of 0.66 uM. |
| PC-22285 |
MS-L6
OXPHOS inhibitor
|
MS-L6 is a novel small molecule OXPHOS inhibitor, exerts dual mitochondrial effects: mitochondrial electron transport chain complexe ETC-I inhibition and uncoupling of OXPHOS. |
| PC-22262 |
Fatostatin
SREBP inhibitor
|
Fatostatin is a small molecule sterol regulatory element binding protein (SREBP) inhibitor, impairs the activation process of SREBPs, thereby decreasing the transcription of lipogenic genes in cells. |
| PC-22255 |
SC26196
D6D inhibitor
|
SC26196 (SC-26196) is a potent, selective delta6 desaturase (Δ6 desaturase, D6D, FADS2) inhibitor with IC50 of 0.2 uM in rat liver microsomal assay. |
