Cat. No. |
Product Name |
Information |
PC-35742 |
HB-MIX1902 Supplement (10X)
|
HB-MIX1902 Supplement (10X) is an optimized serum-free supplement used to promote and maintain the growth, maturity and viability of iPS-derived hepatic and biliary cells. MIX1902 is provided as a 10X liquid and is intended to be used with Hepatocyte Culture Medium for optimal viability and prolonged survival of hepatocytes and cholangiocytes. For detaild user guide, please refer to the PC-3574201 User Guide File Below. |
PC-35735 |
NEK6 inibitor 8
|
NEK6 inibitor 8 (ZINC05007751) is a novel inhibitor of the NIMA-related kinase NEK6 with IC50 of 3.4 uM, compound 8 is very selective against NEK1 and NEK6, while no signifcant activity was observed against NEK2, NEK7, and NEK9. |
PC-35723 |
OSMI-4
O-GlcNAc transferase inhibitor
|
OSMI-4 (OGT inhibitor 4b) is a novel potent, selective, cell-active O-linked N-acetylglucosamine transferase (OGT) inhibitor with EC50 of ~3 uM. |
PC-35722 |
OGT inhibitor 4a
O-GlcNAc transferase inhibitor
|
OGT inhibitor 4a (OSMI-4 active form) is a novel potent, selective O-linked N-acetylglucosamine transferase (OGT) inhibitor with Kd of 8 nM, the active form of OSMI-4. |
PC-35706 |
G6PD activator AG1
G6PD activator
|
G6PD activator AG1 (AG1) is a specific, small molecule that increases the activity of the wild-type, Canton mutant (R459L, EC50=3 uM) and several other common glucose-6-phosphate dehydrogenase (G6PD) mutants. |
PC-35697 |
DKFZ-251
KLK6 inhibitor
|
DKFZ-251 (DKFZ251) is a selective inhibitor of Kallikrein-related peptidase 6 (KLK6) with IC50 of 0.13 uM, demonstrates good selectivity for KLK6 compared to other KLKs. |
PC-35685 |
KAN0438241
PFKFB3 inhibitor
|
KAN0438241 (KAN-0438241) is a potent, selective PFKFB3 inhibitor with IC50 of 0.19 uM, 20-fold selectivity over PFKFB4 and no significant inhibition on PFKFB1 and 2. |
PC-35684 |
KAN0438757
PFKFB3 inhibitor
|
KAN0438757 (KAN-0438757) is a potent, selective PFKFB3 inhibitor, the ester prodrug of KAN0438241 with enhanced cell permeability. |
PC-35673 |
WJ460
Myoferlin inhibitor
|
WJ460 (Myoferlin inhibitor WJ460, WJ-460) is a small molecule targeting myoferlin (MYOF), exerts anti-metastatic activity in the nanomolar range in breast cancer cells with IC50 of 43.37 nM in MDA-MB-231 and 36.40 nM in BT549 cells. |
PC-35671 |
DS42450411
Hepcidin inhibitor
|
DS42450411 (DS 42450411, DS-42450411) is a potent, orally active hepcidin production inhibitor with IC50 of 32 nM. |
PC-35660 |
DKFZ-633
KLK6 inhibitor
|
DKFZ-633 (DKFZ633) is a selective inhibitor of Kallikrein-related peptidase 6 (KLK6) with IC50 of 0.25 uM, demonstrates good selectivity for KLK6 compared to other KLKs. |
PC-35656 |
BIO922
PICK1 inhibitor
|
BIO922 (BIO 922, BIO-922) is a small molecule PICK1 inhibitor that specificly blocks the PDZ domain-mediated interaction between GluA2 and PICK1 (IC50=69 nM), blocks the effects of Aβ on synaptic transmission and surface receptors. |