| Cat. No. |
Product Name |
Information |
| PC-21471 |
RTI-263
NPSR agonist
|
RTI-263 (SerPheLysAsn-NH2) is a potent, selective tetrapeptide neuropeptide S receptor (NPSR, GPR154) biased agonist with EC50 of 3.02 nM for hNPSR calcium mobilization. |
| PC-21466 |
IOI-214
|
IOI-214 is a potent inhibitor of LPS-induced inflammatory cytokine production, prevent HF diet-induced NAFLD/MAFLD in vivo. |
| PC-21460 |
Brefeldin A
Golgi trafficking inhibitor
|
Brefeldin A is a lactone antibiotic and a specific inhibitor of protein trafficking, blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. |
| PC-21459 |
NR5A2 inhibitor Cmp3d2
LRH1 (NR5A2) inhibitor
|
NR5A2 inhibitor Cmp3d2 is a specific small molecule inhibitor of NR5A2 (liver receptor homolog-1, LRH-1) with Kd of 1.8 uM in Biacore-based assays, inhibits the transcriptional activity of hLRH-1 with IC50 of 6 uM (G0S2 mRNA level). |
| PC-21458 |
NR5A2 inhibitor Cmp3
LRH1 (NR5A2) inhibitor
|
NR5A2 inhibitor Cpd3 is a specific small molecule inhibitor of NR5A2 (liver receptor homolog-1, LRH-1) with Kd of 1.5 uM in Biacore-based assays, inhibits the transcriptional activity of hLRH-1 with IC50 of 5 uM (G0S2 mRNA level). |
| PC-21438 |
JYFY-001
Copper chelator
|
JYFY-001 is a small molecule copper chelator with moderate selectivity for targeting copper, potently inhibits cancer proliferation. |
| PC-21430 |
WDR91-IN-1
WDR91 inhibitor
|
WDR91-IN-1 is a small molecule ligand of WD40 repeat-containing protein 91 (WDR91) with SPR KD value of 6 uM. |
| PC-21429 |
Dp44mT
Iron chelator
|
Dp44mT is an iron chelator with selective anticancer activity, exhibits wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics. |
| PC-21417 |
HQY436
CPSF3 inhibitor
|
HQY436 is a specific, orally bioavailable inhibitor of pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3 (CPSF3) with binding IC50 of 0.15 uM, exhibits potent antitumor activity. |
| PC-21411 |
AE1 inhibitor 22
Anion exchanger 1 inhibitor
|
AE1 inhibitor 22 is a small molecule inhibitor of the anion exchanger 1 transporter (AE1) with IC50 of 18 uM. |
| PC-21410 |
LY3522348
Ketohexokinase (KHK) inhibitor
|
LY3522348 is a potent, highly selective, oral dual inhibitor of human ketohexokinase isoforms C and A (hKHK-C, hKHK-A) with IC50 of 20 nM and 24 nM, respectively. |
| PC-21409 |
ECF inhibitor 1
ECF transporter inhibitor
|
ECF inhibitor 1 is a specific small molecule inhibitor of energy-coupling factor (ECF) transporters, potentially acting as protein-protein interaction (PPI) modulator. |
