| Cat. No. |
Product Name |
Information |
| PC-26108 |
Py-Pip
Neurolysin activator
|
Py-Pip is a nonpeptide small molecule activator of Neurolysin (Nln), enhances the activity of peptidase neurolysin. |
| PC-26087 |
MKV3
Cu+-ATPases inhibitor
|
MKV3 is a specific, first-in-class, broad spectrum inhibitor of Cu-transporting P-type ATPases targeting P1B-type copper ATPases, binds within the Cu+ entry pocket, thereby blocking Cu+ delivery to the intramembranous transport site, dependently decreases Cu+-stimulated ATPase activity with IC50 of 130 nM for Escherichia coli Cu+-ATPase CopA (EcCopA). |
| PC-26075 |
TeGG
UGT1A1 inhibitor
|
1,2,3,6-Tetragalloylglucose (TeGG) is a substrate competitive inhibitor of UDP-glucuronyltransferase UGT1A1, inhibits UGT1A1-mediated β-estradiol 3-glucuronidation and SN-38 glucuronidation with IC50 of 6.01 uM and 4.31 uM, respectively. |
| PC-26070 |
APL-4098
GCN2 inhibitor
|
APL-4098 is a potent, selective, ATP-binding site competitive GCN2 inhibitor with Ki of 4.39 nM in TR-FRET assays. |
| PC-26065 |
PSMA-617
PSMA inhibitor
|
PSMA-617 (Vipivotide tetraxetan) is a potent, high affinity prostate-specific membrane antigen (PSMA) inhibitor with Ki of 0.37 nM. |
| PC-25996 |
ADAR1i-124
ADAR1 inhibitor
|
ADAR1i-124 is a selective inhibitor of the ADAR1 A-to-I RNA editing activity with in vitro editing IC50 values of 10-30 uM, inhibits the catalytic activities of both ADAR1p150 and ADAR1p110. |
| PC-25994 |
LP-856866
ACSL5 inhibitor
|
LP-856866 (ACSL5i) is a potent, selective inhibitor of Acyl-CoA Synthetase 5 (ACSL5) with IC50 of 4 nM and 8 nM for huamn and mouse ACSL5 in acyl-CoA synthetase (ACS) assays, highly selective against ACSL3. |
| PC-25980 |
AVIL inhibitor Compound A
Advillin inhibitor
|
AVIL inhibitor Compound A (PLH1215) is a specific small molecule actin-binding protein advillin (AVIL)-interacting compound with MST Kd of 6 uM, also blocks AVIL binding to its substrate actin. |
| PC-25859 |
Lysosome inhibitor LLAD
SLC38A9 inhibitor
|
LLAD is a long-term lysosome-targeting anticancer drug, inhibits SLC38A9 in lysosomes and alkalinizes lysosomes, induces apoptosis through long-term lysosomal damage in vivo and in vitro. |
| PC-25807 |
Ciliogenesis inhibitor Nao-3
Ciliogenesis inhibitor
|
Ciliogenesis inhibitor Nao-3 (Naonedin-3) is specific small-molecule inhibitor of ciliogenesis, represses primary ciliogenesis and induces the death of chemoresistant ciliated stem-like cells. |
| PC-25797 |
JPC0661
ΔFOSB inhibitor
|
JPC0661 is a specific small molecule direct inhibitor of AP1 transcription factor ΔdeltaFOSB (ΔFOSB), inhibits FOSB/JUND and ΔFOSB DNA-binding biochemically with IC50 of 9 uM and 52 uM respectively. |
| PC-25682 |
Ferovicin
FERONIA receptor inhibitor
|
Ferovicin is a specific small molecule inhibitor FERONIA (FER) receptor kinase with IC50 of 70 nM, selectively binds to the ATP-binding pocket of the kinase domain of FER and inhibits its kinase activity. |
