| Cat. No. |
Product Name |
Information |
| PC-25184 |
JX-078
LAT1 inhibitor
|
JX-078 is a potent, selective inhibitor of L-type amino acid transporters LAT1 (SLC7A5), inhibits [3H]-L-leucine uptake into HT-29 cells with IC50 of 121 nM, >10-fold selective over in LAT2. |
| PC-25146 |
BI033
BACH1 inhibitor
|
BI033 is a selective small-molecule BTB and CNC homology 1 (BACH1) inhibitor, specifically binds to BACH1 WT with Kd of 9.0 uM, significantly upregulates HO-1 mRNA and protein expression. |
| PC-25105 |
DEL-S1
SLIT2/ROBO1 inhibitor
|
DEL-S1 is a first-in-class small molecule that binds to SLIT2 and disrupts its interaction with ROBO1 with IC50 of 68.8 uM in TR-FRET assays. |
| PC-25013 |
TREM2 agonist C1
TREM2 agonist
|
TREM2 agonist C1 is a structural analog of VG-3927 and small molecule agonist of triggering receptor expressed on myeloid cells 2 (TREM2) with KD of 71.36 uM in MST assays. |
| PC-24950 |
Eloralintide sodium
Amylin receptor agonist
|
Eloralintide sodium (LY3841136) is a selective amylin mimetic and long acting amylin receptor (AMYR) agonist, binds to amylin receptors with high selectivity from calcitonin receptors. |
| PC-24949 |
Eloralintide
Amylin receptor agonist
|
Eloralintide (LY3841136) is a selective amylin mimetic and long acting amylin receptor (AMYR) agonist, binds to amylin receptors with high selectivity from calcitonin receptors. |
| PC-24837 |
NGI-189
Oligosaccharyltransferase inhibitor
|
NGI-189 is a potent, small molecule inhibitor of oligosaccharyltransferase (OST) with IC50 of 0.09 uM. |
| PC-24792 |
VG-3927
TREM2 agonist
|
VG-3927 (I-192) is a highly potent, selective and brain penetrant triggering receptor expressed on myeloid cells 2 (TREM2) agonist. |
| PC-24750 |
SNT-5382
LOXL2 inhibitor
|
SNT-5382 is a potent, selective and irreversible LOXL2 inhibitor with IC50 of 10 nM, exhibits rapid, time-dependent LOXL2 inhibition and competitively binds to the active site of LOXL2. |
| PC-24626 |
RJG-2036
PTGR2 inhibitor
|
RJG-2036 is a potent, selective, covalent prostaglandin reductase 2 (PTGR2) inhibitor with IC50 of 100 nM (human PTGR2), covalently ligands the noncatalytic Y100 and Y265 residues located in the substrate binding pocket. |
| PC-24616 |
ORIC-533
CD73 inhibitor
|
ORIC-533 is a potent, selective, AMP-competitive and orally bioavailable ectonucleotidase CD73 inhibitor. |
| PC-24611 |
CVB4-57
Cx26 hemichannels inhibitor
|
CVB4-57 is a specific, reversible small molecule Connexin26 hemichannel (Cx26 hemichannel), reversibly inhibited the dye uptake at 5 uM without affecting the gap junction communication and barrier function. |
