| Cat. No. |
Product Name |
Information |
| PC-22206 |
UNC-CA2-103
TLK2 inhibitor
|
UNC-CA2-103 is a potent, selective tousled like kinase 2 (TLK2) inhibitor with enzyme IC50 of 18 nM, exhibit excellent selectivity over TLK1 (16% inhibition at 0.5 μM). |
| PC-22176 |
SMS121
CD36 inhibitor
|
SMS121 (SMS-121) is a drug-like small molecule inhibitor of the very long/long chain fatty acid transporter CD36 (FAT, scavenger receptor class B member 3/SCARB3) with binding Kd of 5.57 uM. |
| PC-22137 |
HYPE inhibitor I2.10
HYPE inhibitor
|
HYPE inhibitor I2.10 is a small molecule HYPE (Huntingtin Yeast Interacting Partner E, FICD) enzyme inhibitor with IC50 of 12.1 uM, inhibits HYPE-mediated AMPylation of BiP in vtro. |
| PC-22049 |
ST80
OTUD4-CD73 inhibitor
|
ST-80 is a specific small molecule inhibitor of interaction between CD73 and OTUD4, specifically disrupts proteolytic interaction between CD73 and OTUD4, leading to reinvigoration of cytotoxic CD8+ T cell activities. |
| PC-22048 |
SCD-19
MIF inhibitor
|
SCD-19 is a small molecule migration inhibitory factor (MIF) inhibitor, blocks the induction of pro-inflammatory M1-like phenotype in BMDMs. |
| PC-22011 |
ZZW-115 hydrochloride
NUPR1 inhibitor
|
ZZW-115 (ZZW115) hydrochloride is a potent inhibitor of NUPR1 (Kd=2.1 uM), an intrinsically disordered protein (IDP) with an entirely disordered conformation. |
| PC-21989 |
BRD1732
|
BRD1732 is an ubiquitinated bifunctional small molecule that could be directly ubiquitinated in cells, resulting in dramatic accumulation of inactive ubiquitin monomers and polyubiquitin chains causing broad inhibition of the ubiquitin-proteasome system. |
| PC-21894 |
IDE397
MAT2A inhibitor
|
IDE397 (GSK4362676, GSK-676, IDE397) is a potent, selective small molecule methionine adenosyltransferase 2a (MAT2A) inhibitor, displays broad anti-tumor activity across a panel of MTAP-deleted patient-derived xenografts. |
| PC-21825 |
EC5026
sEH inhibitor
|
EC5026 (BPN-19186) is a potent, selective orally active soluble epoxide hydrolase (sEH) inhibitor with IC50 of 0.04 nM, shows potential for the treatment of neuropathic pain. |
| PC-21800 |
LY3509754
IL-17A inhibitor
|
LY3509754 is a potent, selective and oral small molecule inhibitor of IL-17A with high binding potency(KD=2.14 nM), dose-dependently prevents human IL-17A and IL-17AF from binding human IL-17RA. |
| PC-21745 |
G3BP inhibitor b
G3BP inhibitor
|
G3BP inhibitor b (G3Ib) is a specific, peptide mimetic inhibitor of RNA-binding proteins G3BP1/2 with SPR Kd value of 0.15 uM, blocks the association of G3BP with its binding partners and inhibits condensation of G3BP both in vitro and in live cells. |
| PC-21744 |
G3BP inhibitor a
G3BP inhibitor
|
G3BP inhibitor a (G3Ia) is a specific, peptide mimetic inhibitor of RNA-binding proteins G3BP1/2 with SPR Kd value of 0.54 uM, blcoks the association of G3BP with its binding partners and inhibits condensation of G3BP both in vitro and in live cells. |
