| Cat. No. |
Product Name |
Information |
| PC-38425 |
Utreloxastat
α-synuclein inhibitor
|
Utreloxastat is a small molecule with potential for suppressing and treating α-synucleinopathies, tauopathies, and other disorders. |
| PC-38422 |
Sirpiglenastat
Glutamine antagonist
|
DRP-104 (Sirpiglenastat) is a novel broad acting glutamine antagonist, has significant anticancer activity by directly targeting tumor metabolism and simultaneously inducing a potent antitumor immune response. |
| PC-38412 |
Phevamine A
Virulence factor
|
Phevamine A is a widely distributed virulence factor in phytopathogens, Phevamine A promotes bacterial growth by suppressing plant immune responses. |
| PC-38411 |
BRD8518
TRIB1 inducer
|
BRD8518 is a specific small molecule TRIB1 inducer, modulates expression of the key genes involved in VLDL production and in LDL clearance in HepG2 cells. |
| PC-38410 |
BRD0418
TRIB1 inducer
|
BRD0418 is a specific small molecule that upregulate TRIB1 expression and phenocopy the effects of TRIB1 cDNA overexpression (EC50=1 uM, TRIB1 overexpression in HepG2 cells). |
| PC-38407 |
RJW100
LRH-1 (NR5A2) agonist
|
RJW100 (RJW 100) is a phospholipid mimetic as liver receptor homolog-1 (LRH-1, NR5A2) agonist with pEC50 of 6.6 and 7.5 for (LRH-1) and steroidogenic factor-1 (SF-1, NR5A1), respectively. |
| PC-38400 |
Inaxaplin
APOL1 inhibitor
|
Inaxaplin (VX-147, VX147) is a small molecule inhibitor of apolipoprotein L1 (APOL1) channel function, shows potential for treatment of proteinuric kidney disease. |
| PC-38392 |
Farudodstat
DHODH inhibitor
|
Farudodstat (ASLAN003) is a highly potent, selective dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 35 nM (human DHODH), significantly inhibits protein synthesis via activation AP-1 transcription, induces cell differentiation of AML cell lines. |
| PC-38385 |
Osilodrostat
CYP11 B2 inhibitor
|
Osilodrostat (LCI 699) is a potent, orally active inhibitor of human 11β-hydroxylase and aldosterone synthase with IC50 of 2.5 and 0.7 nM, respectively. |
| PC-38384 |
Baxdrostat
CYP11 B2 inhibitor
|
Baxdrostat (CIN-107, RO6836191) is a highly potent, selective, and competitive small molecule inhibitor of aldosterone synthase (CYP11 B2, steroid 18-hydroxylase) with Ki of 13 nM, >100-fold over 11β-hydroxylase. |
| PC-38369 |
Pirepemat
cognition-promoting agent
|
Pirepemat (IRL752) is a new phenyl-pyrrolidine derivative and cognition-promoting agent with regioselective central nervous system transmission-enhancing properties, enhances norepinephrine, dopamine, and acetylcholine neurotransmission in the cerebral cortex. |
| PC-73459 |
Abimtrelvir
Antiviral
|
Abimtrelvir is a novel antiviral agent. |
