| Cat. No. |
Product Name |
Information |
| PC-38593 |
Synucleozid hydrochloride
α-synuclein inhibitor
|
Synucleozid hydrochloride (NSC 377363) is a small molecule that targets the IRE structure and inhibits SNCA gene translation in cells, directly targets the α-synuclein mRNA 5'UTR at the designed site. |
| PC-38581 |
HyT36
Hydrophobic tag
|
HyT36 is a small-molecule hydrophobic tag compound for the degradation of stabilized proteins, induces an acute, resolvable ER stress that results in transient UPR activation without induction of apoptosis in ERHT-expressing cells. |
| PC-38576 |
ElteN378
FKBP12 inhibitor
|
ElteN378 is a highly potent synthetic inhibitor of FKBP12 with Ki of 0.5 nM, a low atomic weight ligand with affinity comparable to that of the macrolide Rapamycin |
| PC-38564 |
PKN3 inhibitor 16
PKN3 inhibitor
|
PKN3 inhibitor 16 is a potent, cell active protein kinase novel 3 (PKN3) inhibitor with biochemical IC50 of 14 nM, celluar IC50 of 1.3 uM. |
| PC-38552 |
EC23
|
EC23 (AGN190205) is a photostable synthetic retinoid and analog of ATRA, potently induces neural differentiation in human pluripotent embryonic stem cells. |
| PC-38546 |
DL5H3
|
DL5H3 is a bioactive compound with antiasthmatic activity. |
| PC-38539 |
KLH45
DDHD2 inhibitor
|
KLH45 is a potent, selective and in vivo-active serine hydrolase DDHD2 inhibitor with IC50 of 1.3 nM, shows excellent selectivity against other serine hydrolases with exception of ABHD6. |
| PC-38530 |
NCGC607
GCase activator
|
NCGC00241607 (NCGC607) is a small-molecule noninhibitory chaperone of glucocerebrosidase (GCase), successfully chaperoned the mutant enzyme, restored GCase activity and protein levels, and reduced glycolipid storage in neurons. |
| PC-38529 |
pythiDC
CP4H1 inhibitor
|
pythiDC is a small molecule inhibitor of human CP4H1 with IC50 of 4.0 uM, inhibits CP4H activity in cultured cells at concentrations that do not cause iron deficiency. |
| PC-38525 |
ML198
GCase chaperone
|
ML198 is a non-inhibitory chaperone of glucocerebrosidase (GCase) enzyme, does not inhibit the enzyme’s action, but can facilitate its translocation to the lysosome. |
| PC-38518 |
MSBN
|
MSBN is a highly selective fluorogenic probe for thiols, selectively imaging thiols in live cells and specifically label protein thiols with a turn-on signal to determine diverse reversible protein thiol modifications. |
| PC-38516 |
GSK106
PAD4 inhibitor
|
GSK106 is an inactive control for the selective PAD4 inhibitors, GSK484 and GSK199. |
