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Cat. No. Product Name Information
PC-38392

Farudodstat

DHODH inhibitor

Farudodstat (ASLAN003) is a highly potent, selective dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 35 nM (human DHODH), significantly inhibits protein synthesis via activation AP-1 transcription, induces cell differentiation of AML cell lines.
PC-38385

Osilodrostat

CYP11 B2 inhibitor

Osilodrostat (LCI 699) is a potent, orally active inhibitor of human 11β-hydroxylase and aldosterone synthase with IC50 of 2.5 and 0.7 nM, respectively.
PC-38384

Baxdrostat

CYP11 B2 inhibitor

Baxdrostat (CIN-107, RO6836191) is a highly potent, selective, and competitive small molecule inhibitor of aldosterone synthase (CYP11 B2, steroid 18-hydroxylase) with Ki of 13 nM, >100-fold over 11β-hydroxylase.
PC-38369

Pirepemat

cognition-promoting agent

Pirepemat (IRL752) is a new phenyl-pyrrolidine derivative and cognition-promoting agent with regioselective central nervous system transmission-enhancing properties, enhances norepinephrine, dopamine, and acetylcholine neurotransmission in the cerebral cortex.
PC-73459

Abimtrelvir

Antiviral

Abimtrelvir is a novel antiviral agent.
PC-73455

Vutiglabridin

Insulin sensitizer

Vutiglabridin (HSG4112) is a synthetic structural analog of glabridin and insulin sensitizer, novel anti-obesity agent.
PC-73418

Feniralstat

Kallikrein inhibitor

Feniralstat (KVD-824) is a potent, selective kallikrein inhibitor with IC50 of 6.7 nM for human plasma kallikrein (pKal), dispays no inhibition against human KLKl, FXIa and Factor Xlla (IC50>40 uM).
PC-73396

CB253

r(G4C2)exp inhibitor

CB253 is a small molecule that selectively binds the hairpin form of r(G4C2)exp, inhibiting mechanisms that drive c9ALS/FTD pathobiology.
PC-73386

PRG-A01

SOD1 inhibitor

PRG-A01 is a chemical inhibitor against SOD1 misfolding and aggregation, inhibits the neuronal cell death caused by mutant-SOD1 overexpression.
PC-73365

SpiD7

UPR activator

SpiD7 is a spirocyclic dimer compound that activates the unfolded protein response (UPR), selectively inhibits growth and induce apoptosis of cancer cells.
PC-73362

4BPPNit

Glycosylation modulator

4BPPNit is a small molecule significantly augmented glycosylation of α-dystroglycan, in part through upregulation of LARGE1 glycosyltransferase gene expression.
PC-73358

Mito-C

NEET protein inhibitor

Mito-C is a specific chemical compound targeting NEETs proteins, induces mitochondrial network fragmentation and represses dengue viral replication.

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