| Cat. No. |
Product Name |
Information |
| PC-42350 |
TPPU
sHE inhibitor
|
TPPU is a potent soluble epoxide hydrolase (sHE) inhibitor with IC50 of 37 nM and 3.7 nM for monkey and human sHE, respectively. |
| PC-63145 |
Verdiperstat
|
Verdiperstat (AZD-3241) is a potent, selective, reversible, orally active myeloperoxidase (MPO) inhibitor with IC50 of 630 nM, >14-fold selectivity over thyroid peroxidase (TPO). |
| PC-63120 |
MIF-IN-3bb
MIF inhibitor
|
MIF-IN-3bb is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 57 nM. |
| PC-63119 |
Orita-13
MIF inhibitor
|
Orita-13 is potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 17 uM. |
| PC-63118 |
ISO-66
MIF inhibitor
|
ISO-66 is a novel, highly stable, small-molecule MIF inhibitor that inhibits MIF tautomerase activity with IC50 of 1.4 uM. |
| PC-63111 |
CE3F4
|
CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity. |
| PC-63109 |
ESI-05
|
ESI-05 is a potent EAPC2-specific antagonist that inhibits cAMP-mediated EPAC2 GEF activity with apparent IC50 of 0.43 uM. |
| PC-63107 |
NSC 45576
EPAC inhibitor
|
NSC 45576 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 1.7 uM. |
| PC-63105 |
HJC 0726
|
HJC 0726 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor, inhibits cAMP-mediated EPAC2 GEF activity with IC50 of 1.0 uM. |
| PC-62954 |
K-604
|
K-604 is a potent, selective and competitive ACAT-1 inhibitor with IC50 of 0.45 uM for human ACAT-1, displays 229-fold selectivity over ACAT-2. |
| PC-62880 |
DDD85646
NMT1/NMT2 inhibitor
|
DDD 85646 is a potent, specific, dual N-Myristoyltransferase NMT1/NMT2 inhibitor with IC50 of 17 nM/22 nM respectively. |
| PC-62875 |
STK16-IN-1
|
STK16-IN-1 is a potent, highly selective ATP competitive STK16 inhibitor with IC50 of 0.295 uM, displays excellent selectivity across the kinome. |
