SST0871AA1 | Heparanase inhibitor | Probechem Biochemicals

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Chemical Structure : SST0871AA1

SST0871AA1 (SST 0871AA1)

Catalog No.: PC-73269Not For Human Use, Lab Use Only.

SST0871AA1 is a small molecule Heparanase (Hpse) inhibitor with IC50 of 0.64 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SST0871AA1 is a small molecule Heparanase (Hpse) inhibitor with IC50 of 0.64 uM.
SST0871AA1 decreases the in vitro invasive ability of human cancer cell lines.
SST0871AA1 inhibits expression of genes encoding for proangiogenic factors such as MMP-9, VEGF, and FGFs in tumor cells.
SST0871AA1 does not affect cell proliferation.

Physicochemical Properties

M.Wt	660.500
Formula	C32H27BrFN5O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(2-(2-(4-((4-(3-bromo-4-methoxybenzamido)benzyl)amino)-3-fluorophenyl)-1H-benzo[d]imidazol-5-yl)acetyl)glycine

References

1. Madia, V. N. et al. J. Med. Chem. 2018, 61, 6918– 6936.

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SST0871AA1 (SST 0871AA1)

Biological Activity

Physicochemical Properties

References

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