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Hi 76-0079

Chemical Structure : Hi 76-0079

CAS No.: 374567-94-9

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Hi 76-0079 (NNC0076-0079, 76-0079)

Catalog No.: PC-73185Not For Human Use, Lab Use Only.

Hi 76-0079 (NNC0076-0079) is a specfic, small molecule inhibitor of hormone-sensitive lipase (HSL) with IC50 of 0.11 uM.

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5 mg $58 In stock
10 mg $88 In stock
25 mg $148 In stock
50 mg $238 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Hi 76-0079 (NNC0076-0079) is a specfic, small molecule inhibitor of hormone-sensitive lipase (HSL) with IC50 of 0.11 uM.
Hi 76-0079 does not affect ATGL or other lipases (IC50>50 uM).
Hi 76-0079 inhibits lipolysis in vivo.

Physicochemical Properties

M.Wt 256.686
Formula C11H13ClN2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Carbamic acid, 4-morpholinyl-, 4-chlorophenyl ester

References

1. Martina Schweiger, et al. J Biol Chem. 2006 Dec 29;281(52):40236-41.

2. Alsted TJ, et al. Am J Physiol Endocrinol Metab. 2009 Mar;296(3):E445-53.

3. Sakai K, et al. J Lipid Res. 2014 Oct;55(10):2033-40.

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