Chemical Structure : Hi 76-0079
CAS No.: 374567-94-9
Catalog No.: PC-73185Not For Human Use, Lab Use Only.
Hi 76-0079 (NNC0076-0079) is a specfic, small molecule inhibitor of hormone-sensitive lipase (HSL) with IC50 of 0.11 uM.
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Hi 76-0079 (NNC0076-0079) is a specfic, small molecule inhibitor of hormone-sensitive lipase (HSL) with IC50 of 0.11 uM.
Hi 76-0079 does not affect ATGL or other lipases (IC50>50 uM).
Hi 76-0079 inhibits lipolysis in vivo.
M.Wt | 256.686 | |
Formula | C11H13ClN2O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Carbamic acid, 4-morpholinyl-, 4-chlorophenyl ester |
1. Martina Schweiger, et al. J Biol Chem. 2006 Dec 29;281(52):40236-41.
2. Alsted TJ, et al. Am J Physiol Endocrinol Metab. 2009 Mar;296(3):E445-53.
3. Sakai K, et al. J Lipid Res. 2014 Oct;55(10):2033-40.
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