| Cat. No. |
Product Name |
Information |
| PC-60594 |
Dihydromunduletone
GPR56 INHIBITOR
|
Dihydromunduletone is a rotenoid derivative that selectively inhibits GPR56 (IC50=21 uM) and GPR114/ADGRG5, but not GPR110 or Class A GPCRs. |
| PC-60514 |
Fulacimstat
Chymase inhibitor
|
Fulacimstat (BAY 1142524, BAY1142524) is a potent, orally available chymase inhibitor with IC50 of 4 nM and 3 nM for human and hamster chymase enzyme, respectively. |
| PC-70232 |
NAPQI
MIF inhibitor
|
NAPQI (N-Acetylimidoquinone) is a toxic byproduct, iminoquinone metabolite of acetaminophen that covalently binds to the active site of macrophage migration inhibitory factor (MIF). |
| PC-70231 |
KIN-1148
IRF3 agonist
|
KIN-1148 (KIN1148) is a small-molecule IRF3 agonist that induces dose-dependent IRF3 nuclear translocation and specific activation of IRF3-responsive promoters. |
| PC-70227 |
WOBE-437
|
WOBE-437 (WOBE437) is a potent, selective endocannabinoid uptake inhibitor with IC50 of 10 nM, with an outstanding 1,000-fold selectivity over FAAH. |
| PC-60421 |
SCB-4380
PTPRZ inhibitor
|
SCB-4380 (SCB 4380, SCB4380) is the first potent, selective inhibitor for PTPRZ (protein tyrosine phosphatase receptor-type Z) with IC50 of 0.4 uM against human Z-ICR-catalyzed hydrolysis. |
| PC-60419 |
Compound L
|
Compound L (Ku70/80 inhibitor) is a novel small molecule inhibitor of the DNA repair protein Ku70/80, disrupts of Ku70/80-DNA interaction with IC50 of 3.5 uM in EMSA assay. |
| PC-60393 |
PBD-150
|
PBD150 is a potent glutaminyl cyclase (QC) inhibitor with Ki of 60 nM. |
| PC-70211 |
LY-345899
|
LY-345899 (LY345899) is a novel potent, cytoplasmic and mitochondrial methylenetetrahydrofolate dehydrogenase MTHFD1 and MTHFD2 inhibitor with IC50 of 96 nM and 663 nM, respectively. |
| PC-70176 |
MDL72527
Polyamine oxidase inhibitor
|
MDL72527 is a polyamine oxidase (PAO) inhibitor that inhibits spermine oxidase and N1-acetylpolyamine oxidase with IC50 of 6.1 and 0.02 uM, respectively. |
| PC-70126 |
FPH2
|
FPH2 (BRD-9424) is a small molecule that promotes differentiation of iPS-derived hepatocytes, induces functional proliferation of hepatocytes in vitro, and thus expands mature human primary hepatocytes. |
| PC-70112 |
ATR-101
|
ATR-101 (PD-132301, Nevanimibe) is a selective and potent inhibitor of ACAT1 with IC50 of 52 nM. |
