I-OMe-AG-538 | PI5P4Kα inhibitor | Probechem Biochemicals

Chemical Structure : I-OMe-AG-538

CAS No.: 1094048-77-7

I-OMe-AG-538 (I-OMe-Tyrphostin AG 538)

Catalog No.: PC-72465Not For Human Use, Lab Use Only.

I-OMe-AG-538 (I-OMe-Tyrphostin AG 538) is an ATP-competitive inhibitor of PI5P4Kα with an IC50 of 1 uM, also inhibits the PIP4K2A activity with IC50 of 2.1 uM.

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$218	In stock
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Biological Activity

I-OMe-AG-538 (I-OMe-Tyrphostin AG 538) is an ATP-competitive inhibitor of PI5P4Kα with an IC50 of 1 uM, also inhibits the PIP4K2A activity with IC50 of 2.1 uM.

Physicochemical Properties

M.Wt	437.18
Formula	C17H12INO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-2-(3,4-dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5-methoxyphenyl)prop-2-enenitrile

References

1. Mindy I Davis, et al. PLoS One. 2013;8(1):e54127.

2. Mayumi Kitagawa, et al. Nat Commun. 2017 Dec 19;8(1):2200.

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I-OMe-AG-538 (I-OMe-Tyrphostin AG 538)

Biological Activity

Physicochemical Properties

References

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