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CPSF3 inhibitor 2

Chemical Structure : CPSF3 inhibitor 2

CAS No.: 763907-11-5

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CPSF3 inhibitor 2

Catalog No.: PC-72477Not For Human Use, Lab Use Only.

CPSF3 inhibitor 2 is a small moleculemodulator of pre-mRNA processing, targets and binds to human CPSF3 (Kd=370 nM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CPSF3 inhibitor 2 is a small moleculemodulator of pre-mRNA processing, targets and binds to human CPSF3 (Kd=370 nM).
    CPSF3 inhibitor 2 mimics pre-mRNA binding to CPSF3, inhibiting its endonuclease activity and conferring growth inhibitory effects.

    Physicochemical Properties

    M.Wt 496.385
    Formula C23H27Cl2N3O5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (3,5-dichloro-2-hydroxy-4-(2-(4-methylpiperazin-1-yl)ethoxy)benzoyl)-L-phenylalanine

    References

    1. Ross NT, et al. Nat Chem Biol. 2020 Jan;16(1):50-59.

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