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Cat. No. Product Name Information
PC-73143

MCU-i11

MICU1 inhibitor

MCU-i11 is a specific MICU1 targeting compound that negative modulate mitochondrial Ca2+ uptake.
PC-73142

MCU-i4

MICU1 inhibitor

MCU-i4 is a specific MICU1 targeting compound that negative modulate mitochondrial Ca2+ uptake.
PC-73139

ASN90

O-GlcNAcase inhibitor

ASN90 is a potent, selective, substrate-competitive O-GlcNAcase (OGA) inhibitor with IC50 of 10.2 nM.
PC-73138

KVD900

Plasma kallikrein inhibitor

Sebetralstat (KVD900) is a potent, selective, competitive and reversible inhibitor of human plasma kallikrein (PKa) enzyme with Ki of 3.02 nM.
PC-73136

Naphthyridine-azaquinolone

Slipped-CAG DNA binder

Naphthyridine-azaquinolone (NA) is a specific small molecule that specifically binds slipped-CAG DNA intermediates of expansion mutations.
PC-73135

PGAM1 inhibitor KH3

PGAM1 inhibitor

PGAM1 inhibitor KH3 is a potent, allosteric small molecule inhibitor of phosphoglycerate mutase 1 (PGAM1) with IC50 of 105 nM.
PC-73129

HG106

SLC7A11 inhibitor

HG106 (HG 106) is a potent, selective SLC7A11 inhibitor, selectively kills KRAS-mutant lung adenocarcinoma (LUAD) cells.
PC-73123

CU-76

cGAS inhibitor

CU-76 (cGAS inhibitor CU-76) is a small-molecule human cGAS (hcGAS) inhibitor with IC50 of 0.24 uM.
PC-73115

AZD9898

LTC4S inhibitor

AZD9898 (AZD-9898) is a highly potent, selective and oral inhibitor of leukotriene C4 synthase (LTC4S) with IC50 of 0.28 nM.
PC-73111

S-181

GCase activator

S-181 (S 181) is a specific small-molecule activator (modulator) of β-glucocerebrosidase (GCase) with AC50 of 1.49 uM and a maximum activation of 780%.
PC-73103

GNF362

ITPKB inhibitor

GNF362 (GNF-362) is a highly potent, selective inhibitor of inositol 1,4,5-trisphosphate 3-kinase B (ITPKB) with IC50 of 9 nM.
PC-73101

VIT-2763

Ferroportin inhibitor

VIT-2763 (Vamifeport, VIT2763) is an oral small molecule inhibitor of ferroportin, inhibits hepcidin binding to ferroportin with IC50 of 9 nM, blocks iron efflux.

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