| Cat. No. |
Product Name |
Information |
| PC-38385 |
Osilodrostat
CYP11 B2 inhibitor
|
Osilodrostat (LCI 699) is a potent, orally active inhibitor of human 11β-hydroxylase and aldosterone synthase with IC50 of 2.5 and 0.7 nM, respectively. |
| PC-38384 |
Baxdrostat
CYP11 B2 inhibitor
|
Baxdrostat (CIN-107, RO6836191) is a highly potent, selective, and competitive small molecule inhibitor of aldosterone synthase (CYP11 B2, steroid 18-hydroxylase) with Ki of 13 nM, >100-fold over 11β-hydroxylase. |
| PC-38369 |
Pirepemat
cognition-promoting agent
|
Pirepemat (IRL752) is a new phenyl-pyrrolidine derivative and cognition-promoting agent with regioselective central nervous system transmission-enhancing properties, enhances norepinephrine, dopamine, and acetylcholine neurotransmission in the cerebral cortex. |
| PC-73459 |
Abimtrelvir
Antiviral
|
Abimtrelvir is a novel antiviral agent. |
| PC-73455 |
Vutiglabridin
Insulin sensitizer
|
Vutiglabridin (HSG4112) is a synthetic structural analog of glabridin and insulin sensitizer, novel anti-obesity agent. |
| PC-73418 |
Feniralstat
Kallikrein inhibitor
|
Feniralstat (KVD-824) is a potent, selective kallikrein inhibitor with IC50 of 6.7 nM for human plasma kallikrein (pKal), dispays no inhibition against human KLKl, FXIa and Factor Xlla (IC50>40 uM). |
| PC-73396 |
CB253
r(G4C2)exp inhibitor
|
CB253 is a small molecule that selectively binds the hairpin form of r(G4C2)exp, inhibiting mechanisms that drive c9ALS/FTD pathobiology. |
| PC-73386 |
PRG-A01
SOD1 inhibitor
|
PRG-A01 is a chemical inhibitor against SOD1 misfolding and aggregation, inhibits the neuronal cell death caused by mutant-SOD1 overexpression. |
| PC-73365 |
SpiD7
UPR activator
|
SpiD7 is a spirocyclic dimer compound that activates the unfolded protein response (UPR), selectively inhibits growth and induce apoptosis of cancer cells. |
| PC-73362 |
4BPPNit
Glycosylation modulator
|
4BPPNit is a small molecule significantly augmented glycosylation of α-dystroglycan, in part through upregulation of LARGE1 glycosyltransferase gene expression. |
| PC-73358 |
Mito-C
NEET protein inhibitor
|
Mito-C is a specific chemical compound targeting NEETs proteins, induces mitochondrial network fragmentation and represses dengue viral replication. |
| PC-73311 |
FQI1
LSF inhibitor
|
Factor quinolinone inhibitor 1 (FQI1) is a small molecule inhibitor of transcription factor Late SV40 Factor (LSF), inhibits LSF DNA-binding activity both in vitro and in cells (IC50=2.1 uM). |
